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Query: CDC40

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDC40 1 2.824 -1.360 3.020 1.080 -0.487 0.013

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDC40 Phosphorylation S43 -0.705 -0.097 _S(ph)PSSKPSLAVAVDSAPEVAVK_

Background Information for CDC40:


Pubmed-CDC40 »
Uniprot-CDC40 »
Biogrid-CDC40 »
ProteomicsDB-CDC40 »

Tumorportal-CDC40 »
COSMIC-CDC40 »
GenomeRNAi-CDC40 »
Genecards-CDC40


Protein-protein Interactions for CDC40
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC12 Cat. description Hein, Mann, Cell 2015
Category members IP bait CRNKL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ISY1;RAB43 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNW1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C16orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHX8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1143 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFDN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALYL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDC40
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring CDC40
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring CDC40
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members Pathway Pathway_852 REACTOME_MRNA_3_END_PROCESSING 0 2.02
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0031124 mRNA 3'-end processing Database 0.91
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87


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