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Query: MTR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTR 0 0.356 -0.880 0.640

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTR Ubiquitylation K814 -0.284 _VIDLGVMTPCDK(gl)ILK_
MTR Ubiquitylation K817 -1.172 -0.641 _ILK(gl)AALDHK_
MTR Ubiquitylation K865 -0.805 _IPLLIGGATTSK(gl)THTAVK_
MTR Ubiquitylation K1000 -0.505 -0.872 _IFNDK(gl)TVGGEAR_
MTR Ubiquitylation K735 -1.046 _MFLPQVIK(gl)SAR_
MTR Ubiquitylation K139 -1.097 _KAAEEVTLQTGIK(gl)R_
MTR Ubiquitylation K151 -1.770 _FVAGALGPTNK(gl)TLSVSPSVERPDYR_

Background Information for MTR:


Pubmed-MTR »
Uniprot-MTR »
Biogrid-MTR »
ProteomicsDB-MTR »

Tumorportal-MTR »
COSMIC-MTR »
GenomeRNAi-MTR »
Genecards-MTR


Protein-protein Interactions for MTR
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait AKAP13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM196A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IQCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPCAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA5L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTR
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members S_MeTrfase IPR003726 0.02
Category members Cobalamin-bd IPR006158 0


Protein complexes (CORUM database) featuring MTR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MTR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Disease phenotype HOMOCYSTEINEMIA HOMOCYSTEINEMIA Database 0.53
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members Disease phenotype NEURAL_TUBE_DEFECTS_FOLATE-SENSITIVE NEURAL TUBE DEFECTS FOLATE-SENSITIVE Database 0.23
Category members GO Category GO:0009086 methionine biosynthetic process Database 0.17
Category members GO Category GO:0000096 sulfur amino acid metabolic process Database 0.15
Category members Pathway Pathway_275 KEGG_ONE_CARBON_POOL_BY_FOLATE 0 0.11
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members GO Category GO:0031419 cobalamin binding Database 0.06
Category members Pathway Pathway_400 KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 0 0.04
Category members GO Category GO:0008898 homocysteine S-methyltransferase activity Database 0.02
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_399 REACTOME_SULFUR_AMINO_ACID_METABOLISM 0 0
Category members Pathway Pathway_82 REACTOME_PHASE_II_CONJUGATION 0 0
Category members Pathway Pathway_85 REACTOME_BIOLOGICAL_OXIDATIONS 0 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0009235 cobalamin metabolic process Database 0
Category members GO Category GO:0032259 methylation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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