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Query: LDHC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LDHC 1 2.406 0.660 0.360
LDHC 1 2.406 0.660 0.360 -0.305 2.399 -2.477 0.419 0.686

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LDHC Ubiquitylation K308 -0.099 0.921 _GLTSVINQK(gl)LKDDEVAQLK_
LDHC Ubiquitylation K82 0.531 _IVADK(gl)DYSVTANSK_
LDHC Ubiquitylation K329 0.419 _SADTLWDIQK(gl)DLKDL_
LDHC Ubiquitylation K5 0.146 _(ac)STVK(gl)EQLIEK_
LDHC Ubiquitylation K81 -0.271 _ITSGK(gl)DYSVSANSR_
LDHC Ubiquitylation K7 -0.548 _EK(gl)LIAPVAEEEATVPNNK_
LDHC Ubiquitylation K310 0.087 -0.793 _LK(gl)DDEVAQLKK_
LDHC Ubiquitylation K318 -0.094 -1.111 _LKDDEVAQLK(gl)K_
LDHC Ubiquitylation K332 0.762 _SADTLWDIQKDLK(gl)DL_

Background Information for LDHC:


Pubmed-LDHC »
Uniprot-LDHC »
Biogrid-LDHC »
ProteomicsDB-LDHC »

Tumorportal-LDHC »
COSMIC-LDHC »
GenomeRNAi-LDHC »
Genecards-LDHC


Protein-protein Interactions for LDHC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ELMOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LDHA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LDHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LDHC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Lactate/malate_DH_N IPR001236 0.19
Category members L-lactate/malate_DH IPR001557 0.19
Category members L-lactate_DH IPR011304 0.08
Category members Lactate_DH/Glyco_Ohase_4_C IPR015955 0.04
Category members Lactate/malate_DH_C IPR022383 0.04


Protein complexes (CORUM database) featuring LDHC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LDHC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006096 glycolysis Database 2.49
Category members Pathway Pathway_28 KEGG_PROPANOATE_METABOLISM 0 1.89
Category members Pathway Pathway_16 KEGG_PYRUVATE_METABOLISM 0 1.34
Category members Pathway Pathway_402 BIOCARTA_SARS_PATHWAY 0 0.64
Category members GO Category GO:0044262 cellular carbohydrate metabolic process Database 0.64
Category members GO Category GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Database 0.29
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0019244 lactate biosynthetic process from pyruvate Database 0.09
Category members GO Category GO:0004459 L-lactate dehydrogenase activity Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0006090 pyruvate metabolic process Database 0.04
Category members Pathway Pathway_400 KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 0 0.04
Category members GO Category GO:0006754 ATP biosynthetic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0030317 sperm motility Database 0
Category members GO Category GO:0031514 motile cilium Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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