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Query: CTBP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTBP2 1 2.554 2.270 -1.110
CTBP2 1 2.554 2.270 -1.110 1.494 -0.398 0.504 0.897 -0.123

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CTBP2 Ubiquitylation K6 0.873 0.855 _(ac)ALVDK(gl)HK_
CTBP2 Ubiquitylation K286 0.130 0.008 _ALAQALK(gl)EGR_
CTBP2 Phosphorylation S492 -1.548 _YPPGIVGVAPGGLPAAM(ox)EGIIPGGIPVTHNLPTVAHPS(ph)QAPSPNQPTK_
CTBP2 Ubiquitylation K279 0.443 _GGLVDEK(gl)ALAQALK_

Background Information for CTBP2:


Pubmed-CTBP2 »
Uniprot-CTBP2 »
Biogrid-CTBP2 »
ProteomicsDB-CTBP2 »

Tumorportal-CTBP2 »
COSMIC-CTBP2 »
GenomeRNAi-CTBP2 »
Genecards-CTBP2


Protein-protein Interactions for CTBP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CTBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IGFBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LCOR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB42 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CTBP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members D-isomer_DH_NAD-bd IPR006140 0.03
Category members D-isomer_2_OHA_DH_cat_dom IPR006139 0


Protein complexes (CORUM database) featuring CTBP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 642 CtBP complex Database 3.6
Category members Corum 643 CtBP core complex Database 1.41
Category members Corum 2921 SHARP-CtBP complex Database 0.08


Categories featuring CTBP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0051287 NAD binding Database 1.6
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Database 0.29
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0017053 transcriptional repressor complex Database 0.28
Category members Pathway Pathway_565 KEGG_CHRONIC_MYELOID_LEUKEMIA 0 0.22
Category members GO Category GO:0019079 viral genome replication Database 0.22
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0048037 cofactor binding Database 0.08
Category members GO Category GO:0045202 synapse Database 0.06
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members Pathway Pathway_892 KEGG_NOTCH_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0050872 white fat cell differentiation Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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