bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: SDHA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SDHA 0 0.344 1.350 -1.030 0.223 0.787 0.745
SDHA 0 0.344 1.350 -1.030 0.602 0.333 -0.951 0.718 0.496

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SDHA Ubiquitylation K341 -1.790 _YAPVAK(gl)DLASR_

Background Information for SDHA:


Pubmed-SDHA »
Uniprot-SDHA »
Biogrid-SDHA »
ProteomicsDB-SDHA »

Tumorportal-SDHA »
COSMIC-SDHA »
GenomeRNAi-SDHA »
Genecards-SDHA


Protein-protein Interactions for SDHA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SDHAF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACAD9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDHA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SDHA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FAD_bind_dom IPR003953 0
Category members Fum_Rdtase/Succ_DH_flav-like_C IPR015939 0
Category members Pyr_nucl-diS_OxRdtase_FAD/NAD IPR023753 0


Protein complexes (CORUM database) featuring SDHA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SDHA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members GO Category GO:0006099 tricarboxylic acid cycle Database 2.74
Category members Pathway Pathway_12 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 0 1.87
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_8 BIOCARTA_KREB_PATHWAY 0 1.35
Category members Pathway Pathway_50 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ 0 0.7
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006105 succinate metabolic process Database 0.31
Category members Disease phenotype Gastrointestinal_stromal_tumor Gastrointestinal stromal tumor Database 0.22
Category members Pathway Pathway_49 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT 0 0.17
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0050660 flavin adenine dinucleotide binding Database 0.12
Category members Disease phenotype Familial_isolated_dilated_cardiomyopathy Familial isolated dilated cardiomyopathy Database 0.08
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Disease phenotype Leigh_syndrome_with_leukodystrophy Leigh syndrome with leukodystrophy Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members Disease phenotype Leigh_Syndrome_(nuclear_DNA_mutation) Leigh Syndrome (nuclear DNA mutation) Database 0.04
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members Pathway Pathway_30 KEGG_OXIDATIVE_PHOSPHORYLATION 0 0
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Pathway Pathway_48 BIOCARTA_ETC_PATHWAY 0 0
Category members Disease phenotype Hereditary_pheochromocytoma-paraganglioma Hereditary pheochromocytoma-paraganglioma Database 0
Category members Disease phenotype Isolated_succinate-CoQ_reductase_deficiency Isolated succinate-CoQ reductase deficiency Database 0
Category members Disease phenotype Leigh_syndrome Leigh syndrome Database 0
Category members GO Category GO:0000104 succinate dehydrogenase activity Database 0
Category members GO Category GO:0005749 mitochondrial respiratory chain complex II Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0008177 succinate dehydrogenase (ubiquinone) activity Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors Database 0
Category members GO Category GO:0022900 electron transport chain Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


.

© Copyright Svejstrup Laboratory 2015