Results for the Category
Leigh Syndrome (nuclear DNA mutation)
(Leigh_Syndrome_(nuclear_DNA_mutation))
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| NDUFS1 | 0 | -0.550 | 0.770 | 0.388 | -0.330 | -1.498 | 0.368 | 0.186 |
| SDHA | 0 | 1.350 | -1.030 | 0.223 | 0.787 | 0.745 | ||
| SDHA | 0 | 1.350 | -1.030 | 0.602 | 0.333 | -0.951 | 0.718 | 0.496 |
| DLD | 0 | -0.420 | 0.270 | 1.380 | 0.780 | -1.052 | 0.824 | 0.231 |
| NDUFAF2 | 0 | -0.810 | 0.580 | -0.263 | -0.281 | |||
| NDUFAF2 | 0 | 0.000 | -0.110 | -0.263 | -0.281 | |||
| NDUFS4 | 0 | 0.190 | -0.590 | -0.148 | -0.106 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| NDUFAF2 | Ubiquitylation | K39 | -2.005 | _YYYIPQYK(gl)NWR_ | |
| NDUFS1 | Ubiquitylation | K298 | -1.134 | _FAYDGLK(gl)R_ | |
| SDHA | Ubiquitylation | K341 | -1.790 | _YAPVAK(gl)DLASR_ |
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