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Leigh syndrome with leukodystrophy
(Leigh_syndrome_with_leukodystrophy)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
NDUFS1 0 -0.550 0.770 0.388 -0.330 -1.498 0.368 0.186
SDHA 0 1.350 -1.030 0.223 0.787 0.745
SDHA 0 1.350 -1.030 0.602 0.333 -0.951 0.718 0.496
NDUFS8 0 0.480 0.100 0.556 0.300 0.534
NDUFS7 0 1.220 -0.670 -0.853 -0.390 -1.647
NDUFS7 0 1.220 -0.670 0.036 -0.063
NDUFA10 0 -0.010 -0.040 -0.338 0.377 0.103
NDUFA10 0 -0.010 -0.040 -0.348
NDUFS4 0 0.190 -0.590 -0.148 -0.106
NDUFV1 0 -0.620 0.680 -0.032 0.387
NDUFS3 0 0.810 -0.670 0.563 -0.004 -0.643 0.049 -0.093

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
NDUFS1 Ubiquitylation K298 -1.134 _FAYDGLK(gl)R_
NDUFS8 Ubiquitylation K88 -1.865 _EPATINYPFEK(gl)GPLSPR_
SDHA Ubiquitylation K341 -1.790 _YAPVAK(gl)DLASR_


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