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bioLOGIC Data

Query: NDUFA10

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
NDUFA10	0	-0.206	-0.010	-0.040		-0.348
NDUFA10	0	-0.206	-0.010	-0.040	-0.338			0.377	0.103

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence

Background Information for NDUFA10:

Pubmed-NDUFA10 »

Uniprot-NDUFA10 »

Biogrid-NDUFA10 »

ProteomicsDB-NDUFA10 »

Tumorportal-NDUFA10 »

COSMIC-NDUFA10 »

GenomeRNAi-NDUFA10 »

Genecards-NDUFA10

Protein-protein Interactions for NDUFA10

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait ELMSAN1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait FAM82A2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait GOLT1B	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PLK1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RAB5C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait VAPA	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait B3GNT2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait NDUFA10	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait NDUFB11	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in NDUFA10

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	P-loop_NTPase	IPR027417	2.83
Category members	DNK	IPR002624	0

Protein complexes (CORUM database) featuring NDUFA10

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring NDUFA10

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005524	ATP binding	Database	5.54
Category members	GO Category	GO:0005739	mitochondrion	Database	1.67
Category members	Pathway	Pathway_50	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_	0	0.7
Category members	GO Category	GO:0042493	response to drug	Database	0.66
Category members	GO Category	GO:0005759	mitochondrial matrix	Database	0.59
Category members	Pathway	Pathway_32	KEGG_HUNTINGTONS_DISEASE	0	0.46
Category members	GO Category	GO:0044281	small molecule metabolic process	Database	0.35
Category members	Pathway	Pathway_49	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT	0	0.17
Category members	GO Category	GO:0022904	respiratory electron transport chain	Database	0.15
Category members	GO Category	GO:0005743	mitochondrial inner membrane	Database	0.15
Category members	GO Category	GO:0008137	NADH dehydrogenase (ubiquinone) activity	Database	0.11
Category members	GO Category	GO:0044237	cellular metabolic process	Database	0.08
Category members	Disease phenotype	Leigh_syndrome_with_leukodystrophy	Leigh syndrome with leukodystrophy	Database	0.08
Category members	GO Category	GO:0005747	mitochondrial respiratory chain complex I	Database	0.08
Category members	GO Category	GO:0006139	nucleobase-containing compound metabolic process	Database	0.08
Category members	GO Category	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	Database	0.07
Category members	Pathway	Pathway_13	REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT	0	0.04
Category members	Pathway	Pathway_29	KEGG_ALZHEIMERS_DISEASE	0	0
Category members	Pathway	Pathway_30	KEGG_OXIDATIVE_PHOSPHORYLATION	0	0
Category members	Pathway	Pathway_31	KEGG_PARKINSONS_DISEASE	0	0
Category members	GO Category	GO:0016773	phosphotransferase activity, alcohol group as acceptor	Database	0