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Query: CAMKK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CAMKK1 0 1.676 0.380 0.000

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CAMKK1 Phosphorylation S74 0.752 0.924 _KLS(ph)LQER_
CAMKK1 Phosphorylation S530 0.732 0.456 _EGFGEGGKS(ph)PELPGVQEDEAAS_
CAMKK1 Phosphorylation S82 -0.892 -0.705 _LSLQERPAGS(ph)YLEAQAGPYATGPASHISPR_

Background Information for CAMKK1:


Pubmed-CAMKK1 »
Uniprot-CAMKK1 »
Biogrid-CAMKK1 »
ProteomicsDB-CAMKK1 »

Tumorportal-CAMKK1 »
COSMIC-CAMKK1 »
GenomeRNAi-CAMKK1 »
Genecards-CAMKK1


Protein-protein Interactions for CAMKK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CAMKK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAMKK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0355 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPIN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CAMKK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CAMKK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CAMKK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1167 BIOCARTA_CACAM_PATHWAY 0 0
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_224 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS 0 0
Category members Pathway Pathway_230 REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 0 0
Category members Pathway Pathway_238 REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0004683 calmodulin-dependent protein kinase activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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