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REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS
(Pathway_224)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ACTN2 3 -1.480 2.640 0.936 1.929 -1.407 0.572 0.293
ACTN2 3 -1.480 2.640 0.790 0.055 0.246
CAMK2B 1 1.200 -0.790
CAMK2B 1 1.200 -0.790 -0.654 0.073
CAMK2B 1 1.200 -0.790 -0.619 0.544 0.125
CAMK2B 1 1.200 -0.790 0.559 1.698
RAF1 1 2.020 -1.230
ADCY3 1 -0.850 1.180
CALM2 1 -0.690 0.700 1.911
CALM2 1 -0.690 0.700 0.877 -4.680
CALM3 1 -0.190 0.120 1.911
CALM3 1 -0.190 0.120 0.877 -4.680
RPS6KA3 1 -1.550 2.890
CALM1 1 -0.440 0.360 1.911
CALM1 1 -0.440 0.360 0.877 -4.680
CAMKK1 0 0.380 0.000
CAMK2A 0 -0.430 0.130 -0.654 0.073
CAMK2A 0 -0.430 0.130 -0.619 0.544 0.125
RPS6KA6 0 -1.250 1.770
RPS6KA1 0 -0.160 -0.660
RPS6KA1 0 -0.160 -0.660
CREB1 0 1.080 -0.800 -1.027
PDPK1 0 0.050 -0.440
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487
CAMK2D 0 -0.260 0.500 -0.654 0.073
CAMK2D 0 -0.260 0.500 -0.619 0.544 0.125
CAMK2D 0 -0.260 0.500
CAMK4 0 0.780 -0.790
BRAF 0
HRAS 0 1.470 -0.520

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ACTN2 Ubiquitylation K125 1.906 _ALDFIASKGVK(gl)_
ACTN2 Ubiquitylation K350 0.585 _VQEK(gl)CQLEINFNTLQTK_
ACTN2 Ubiquitylation K417 0.789 _LDHLAEK(gl)FR_
ACTN2 Ubiquitylation K592 -0.644 0.678 _EAILAIHK(gl)EAQR_
ACTN2 Ubiquitylation K760 0.273 1.507 _DAK(gl)GISQEQMQEFR_
ADCY3 Ubiquitylation K406 -0.885 _TK(gl)TGVDMR_
ADCY3 Ubiquitylation K628 0.051 _YSVEK(gl)EK_
ADCY3 Ubiquitylation K879 0.818 2.820 _IEVHDQK(gl)ER_
ADCY3 Ubiquitylation K1047 -1.036 _IGMNK(gl)GGVLAGVIGAR_
BRAF Phosphorylation S151 -0.685 -0.629 _SNPKS(ph)PQKPIVR_
BRAF Phosphorylation S363 -0.023 -0.241 _S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF Phosphorylation S365 -0.286 0.012 _SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF Phosphorylation S399 -0.890 -0.527 _GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF Phosphorylation T401 -0.525 _GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF Phosphorylation S446 0.246 0.349 _RDS(ph)SDDWEIPDGQITVGQR_
BRAF Phosphorylation S447 0.579 0.623 _RDSS(ph)DDWEIPDGQITVGQR_
BRAF Phosphorylation S729 0.208 0.219 _SAS(ph)EPSLNR_
CALM1 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM1 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM2 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM2 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM3 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM3 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CAMK2A Ubiquitylation K251 -0.437 _DLINK(gl)MLTINPAK_
CAMK2B Ubiquitylation K147 -1.064 _DLKPENLLLASK(gl)CK_
CAMK2B Ubiquitylation K251 -0.437 _DLINK(gl)MLTINPAK_
CAMK2D Ubiquitylation K251 -0.437 _DLINK(gl)MLTINPAK_
CAMK2D Phosphorylation S330 0.412 0.370 _KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D Phosphorylation T331 -0.174 _KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D Phosphorylation T336 0.615 0.376 _ESTESSNT(ph)TIEDEDVK_
CAMK2D Phosphorylation T337 0.450 _ESTESSNTT(ph)IEDEDVK_
CAMK4 Phosphorylation S360 -0.256 0.086 _DPS(ph)PIQDGNEDMK_
CAMKK1 Phosphorylation S74 0.752 0.924 _KLS(ph)LQER_
CAMKK1 Phosphorylation S82 -0.892 -0.705 _LSLQERPAGS(ph)YLEAQAGPYATGPASHISPR_
CAMKK1 Phosphorylation S530 0.732 0.456 _EGFGEGGKS(ph)PELPGVQEDEAAS_
CREB1 Phosphorylation S271 -0.979 -1.450 _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1 Ubiquitylation K333 1.343 _ALK(gl)DLYCHK_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
PDPK1 Phosphorylation S241 0.358 0.361 _ANS(ph)FVGTAQYVSPELLTEK_
PDPK1 Ubiquitylation K257 0.571 -0.234 _ANSFVGTAQYVSPELLTEK(gl)SACK_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
RAF1 Phosphorylation S29 0.028 -0.571 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation T31 0.028 -0.669 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation S244 0.053 _YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1 Phosphorylation S259 -0.069 0.054 _STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1 Phosphorylation S301 -0.651 _SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1 Phosphorylation T303 -0.664 _SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1 Phosphorylation S497 -0.449 _SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1 Phosphorylation S621 0.212 0.271 _SAS(ph)EPSLHR_
RAF1 Phosphorylation S642 -0.197 0.463 _AAHTEDINACTLTTS(ph)PR_
RPS6KA1 Phosphorylation S227 0.363 0.496 _AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA1 Phosphorylation T231 0.315 _KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA1 Ubiquitylation K316 -1.156 _LGSGPDGAEEIK(gl)R_
RPS6KA1 Phosphorylation T359 -0.149 -0.339 _T(ph)PKDSPGIPPSAGAHQLFR_
RPS6KA1 Phosphorylation S363 -0.711 -0.697 _TPKDS(ph)PGIPPSAGAHQLFR_
RPS6KA1 Ubiquitylation K566 -0.152 _ICDFGFAK(gl)QLR_
RPS6KA3 Phosphorylation S227 0.363 0.496 _AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA3 Phosphorylation T231 0.315 _KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA3 Ubiquitylation K322 -0.076 -0.376 _LGAGPDGVEEIK(gl)R_
RPS6KA3 Phosphorylation T365 -0.892 -1.003 _T(ph)PKDSPGIPPSANAHQLFR_
RPS6KA3 Phosphorylation S369 -0.621 -0.862 _TPKDS(ph)PGIPPSANAHQLFR_
RPS6KA3 Ubiquitylation K566 -0.152 _ICDFGFAK(gl)QLR_
RPS6KA3 Phosphorylation S715 -0.923 -0.880 _NQS(ph)PVLEPVGR_
RPS6KA6 Phosphorylation S227 0.363 0.496 _AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA6 Phosphorylation T231 0.315 _KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA6 Ubiquitylation K566 -0.152 _ICDFGFAK(gl)QLR_


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