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Query: FLCN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FLCN 0 -1.778 1.070 -0.810

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FLCN Phosphorylation S62 -0.873 -0.905 _AHS(ph)PAEGASVESSSPGPK_

Background Information for FLCN:


Pubmed-FLCN »
Uniprot-FLCN »
Biogrid-FLCN »
ProteomicsDB-FLCN »

Tumorportal-FLCN »
COSMIC-FLCN »
GenomeRNAi-FLCN »
Genecards-FLCN


Protein-protein Interactions for FLCN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C18orf1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPEP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FLCN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDFY3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FLCN
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring FLCN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FLCN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0032007 negative regulation of TOR signaling Database 0.33
Category members GO Category GO:0007043 cell-cell junction assembly Database 0.31
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0001934 positive regulation of protein phosphorylation Database 0.22
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0070373 negative regulation of ERK1 and ERK2 cascade Database 0.1
Category members GO Category GO:0035024 negative regulation of Rho protein signal transduction Database 0.06
Category members GO Category GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Database 0.06
Category members GO Category GO:0032465 regulation of cytokinesis Database 0.05
Category members GO Category GO:0001932 regulation of protein phosphorylation Database 0.04
Category members GO Category GO:0045785 positive regulation of cell adhesion Database 0.04
Category members Pathway Pathway_23 KEGG_RENAL_CELL_CARCINOMA 0 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Disease phenotype RENAL_CELL_CARCINOMA_NONPAPILLARY RENAL CELL CARCINOMA NONPAPILLARY Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0010629 negative regulation of gene expression Database 0
Category members GO Category GO:0030097 hemopoiesis Database 0
Category members GO Category GO:0031929 TOR signaling Database 0
Category members GO Category GO:0032006 regulation of TOR signaling Database 0
Category members GO Category GO:0032008 positive regulation of TOR signaling Database 0
Category members GO Category GO:0035065 regulation of histone acetylation Database 0
Category members GO Category GO:0044291 cell-cell contact zone Database 0
Category members GO Category GO:0051898 negative regulation of protein kinase B signaling Database 0


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