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Query: TMEM189-UBE2V1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMEM189-UB 0 1.149

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMEM189-UBE2V1 Ubiquitylation K129 0.440 0.709 _LMMSK(gl)ENMK_
TMEM189-UBE2V1 Ubiquitylation K42 -0.791 0.215 _ELAALYSPGK(gl)R_
TMEM189-UBE2V1 Ubiquitylation K291 -0.071 0.214 _IYSLK(gl)IECGPK_

Background Information for TMEM189-UBE2V1:


Pubmed-TMEM189-UBE2V1 »
Uniprot-TMEM189-UBE2V1 »
Biogrid-TMEM189-UBE2V1 »
ProteomicsDB-TMEM189-UBE2V1 »

Tumorportal-TMEM189-UBE2V1 »
COSMIC-TMEM189-UBE2V1 »
GenomeRNAi-TMEM189-UBE2V1 »
Genecards-TMEM189-UBE2V1


Protein-protein Interactions for TMEM189-UBE2V1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in TMEM189-UBE2V1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBQ-conjugat_E2 IPR000608 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring TMEM189-UBE2V1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMEM189-UBE2V1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members Pathway Pathway_1043 REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS 0 0.78
Category members Pathway Pathway_975 REACTOME_IL1_SIGNALING 0 0.42
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members Pathway Pathway_826 REACTOME_ACTIVATED_TLR4_SIGNALLING 0 0.21
Category members Pathway Pathway_573 REACTOME_TCR_SIGNALING 0 0.2
Category members Pathway Pathway_527 REACTOME_TOLL_RECEPTOR_CASCADES 0 0.17
Category members Pathway Pathway_797 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION 0 0.12
Category members Pathway Pathway_814 REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE 0 0.05
Category members Pathway Pathway_1056 REACTOME_NOD1_2_SIGNALING_PATHWAY 0 0.04
Category members Pathway Pathway_1052 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX 0 0.04
Category members Pathway Pathway_1166 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING 0 0
Category members Pathway Pathway_504 REACTOME_SIGNALING_BY_ILS 0 0
Category members Pathway Pathway_618 REACTOME_DOWNSTREAM_TCR_SIGNALING 0 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0


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