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Results for the Category
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS
(Pathway_1043)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
MAPK14 2 -0.160 -0.350
TAB3 2 -0.550 1.560 0.022 -0.207
TAB3 2 -0.550 1.560
CASP8 1 1.120 -1.090
HSP90AB1 1 1.280 -1.050 0.283 0.786 -1.175 0.317 0.463
TAB1 1 1.890 -0.670
TAB1 1 1.890 -0.670 1.657
RIPK2 1 -1.740 3.580
TAB2 0 -0.030 -0.580
CYLD 0 -1.250 2.010
NLRP1 0 -0.960 0.730
IKBKB 0 0.400 0.610
CASP2 0 0.980 -1.120
MAP2K6 0 1.270 -0.780
PANX1 0 -0.440 -0.430
BIRC2 0 -0.730 0.440
BIRC2 0 -0.730 0.440
TNFAIP3 0 0.760 -0.500
TMEM189-UB 0
TMEM189-UB 0
MAP3K7 0 -1.120 1.140 -1.048
TXN 0 1.900 -1.090 1.120 0.196 -5.026
APP 0 0.100 -0.260 0.285
BCL2L1 0
BCL2 0 0.910 -0.740
CHUK 0 -0.480

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
APP Ubiquitylation K751 -1.778 -1.280 _HLSK(gl)M(ox)QQNGYENPTYK_
BCL2 Ubiquitylation K22 1.480 _YIHYK(gl)LSQR_
BCL2L1 Ubiquitylation K87 0.026 _EVIPMAAVK(gl)QALR_
BIRC2 Ubiquitylation K15 -0.259 0.307 _(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2 Ubiquitylation K17 -0.259 0.307 _(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2 Ubiquitylation K38 -0.069 _SIMEDSTILSDWTNSNKQK(gl)_
BIRC2 Ubiquitylation K102 -1.755 _LGDSPIQK(gl)HK_
BIRC2 Ubiquitylation K233 -0.511 _LSNWEPK(gl)DDAMSEHR_
BIRC2 Ubiquitylation K410 0.878 _DLVK(gl)QTVQSK_
BIRC2 Ubiquitylation K490 0.305 0.534 _ANVINK(gl)QEHDIIK_
BIRC2 Ubiquitylation K497 -1.934 _ANVINKQEHDIIK(gl)QK_
CASP2 Phosphorylation S340 -0.347 -1.529 _NHAGS(ph)PGCEESDAGKEK_
CASP8 Ubiquitylation K183 1.917 _IINDYEEFSK(gl)ER_
CASP8 Ubiquitylation K461 -2.031 _NMGK(gl)QMPQPTFTLR_
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
CYLD Ubiquitylation K114 -1.068 0.927 _FSLFK(gl)NR_
HSP90AB1 Ubiquitylation K64 0.829 -0.090 _YESLTDPSK(gl)LDSGKELK_
HSP90AB1 Ubiquitylation K69 0.661 0.380 _LDSGK(gl)ELK_
HSP90AB1 Ubiquitylation K72 -1.242 -0.130 _ELK(gl)IDIIPNPQER_
HSP90AB1 Phosphorylation S226 0.404 0.704 _EKEIS(ph)DDEAEEEK_
HSP90AB1 Phosphorylation S255 0.525 0.628 _IEDVGS(ph)DEEDDSGKDKK_
HSP90AB1 Phosphorylation S261 0.520 0.624 _IEDVGSDEEDDS(ph)GKDK_
HSP90AB1 Ubiquitylation K347 0.110 _RAPFDLFENK(gl)K_
HSP90AB1 Ubiquitylation K348 -0.096 _RAPFDLFENKK(gl)_
HSP90AB1 Ubiquitylation K428 0.308 _K(gl)FYEAFSK_
HSP90AB1 Ubiquitylation K435 0.847 0.933 _FYEAFSK(gl)NLK_
HSP90AB1 Ubiquitylation K438 1.021 -0.058 _NLK(gl)LGIHEDSTNR_
HSP90AB1 Ubiquitylation K481 0.811 _MKETQK(gl)SIYYITGESK_
HSP90AB1 Ubiquitylation K491 0.982 1.512 _SIYYITGESK(gl)EQVANSAFVER_
HSP90AB1 Ubiquitylation K531 0.745 1.350 _EFDGK(gl)SLVSVTK_
HSP90AB1 Ubiquitylation K559 0.847 1.549 _AK(gl)FENLCK_
HSP90AB1 Ubiquitylation K565 -0.066 _FENLCK(gl)LMK_
HSP90AB1 Ubiquitylation K573 0.243 0.360 _EILDK(gl)KVEK_
HSP90AB1 Ubiquitylation K574 0.241 0.550 _EILDKK(gl)VEK_
HSP90AB1 Ubiquitylation K623 0.520 1.081 _DNSTMGYM(ox)MAK(gl)K_
IKBKB Ubiquitylation K106 0.253 _K(gl)YLNQFENCCGLR_
IKBKB Phosphorylation S672 0.670 0.244 _GPVSGS(ph)PDSMNASR_
MAP2K6 Phosphorylation T28 -1.813 -0.792 _EAFEQPQTSST(ph)PPRDLDSK_
MAP2K6 Ubiquitylation K232 0.220 _INPELNQK(gl)GYSVK_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
NLRP1 Ubiquitylation K297 -1.598 _SQDPLVK(gl)R_
PANX1 Ubiquitylation K381 0.720 _MDVVDGK(gl)TPMSAEMR_
RIPK2 Ubiquitylation K410 -2.810 _AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2 Phosphorylation S531 0.884 0.839 _SPS(ph)LNLLQNK_
RIPK2 Ubiquitylation K538 -2.659 _SPSLNLLQNK(gl)SM_
TAB1 Phosphorylation S7 -0.170 0.140 _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1 Phosphorylation S16 -0.138 0.069 _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1 Ubiquitylation K186 -1.015 _SYSADGK(gl)GTESHPPEDSWLK_
TAB1 Ubiquitylation K371 0.032 _LSQLGLDAGK(gl)IK_
TAB1 Ubiquitylation K373 -0.007 _LSQLGLDAGKIK(gl)_
TAB2 Phosphorylation S580 -0.075 _S(ph)NSISQIPSLEEMQQLR_
TAB2 Phosphorylation S582 0.331 _SNS(ph)ISQIPSLEEMQQLR_
TAB2 Ubiquitylation K653 -0.519 -0.200 _SIIK(gl)TPK_
TAB3 Phosphorylation S4 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TAB3 Phosphorylation S5 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TMEM189-UBE2V1 Ubiquitylation K42 -0.791 0.215 _ELAALYSPGK(gl)R_
TMEM189-UBE2V1 Ubiquitylation K129 0.440 0.709 _LMMSK(gl)ENMK_
TMEM189-UBE2V1 Ubiquitylation K291 -0.071 0.214 _IYSLK(gl)IECGPK_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
TXN Ubiquitylation K94 0.520 _VGEFSGANK(gl)EK_


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