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PID_IL3_PATHWAY
(Pathway_550)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HDAC1 1 -1.980 4.450
HDAC1 1 -1.980 4.450 -0.122 0.307 0.969 0.094 0.191
PRKACA 0 0.380 -0.680 -1.005 -0.697 0.234 0.487
PIK3CA 0
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487
SRP9 0 -0.690 0.840 -0.559 -0.644 0.111 -0.103
PIK3R1 0 1.910 -1.220 -0.441 0.147
YWHAZ 0 0.880 -0.450 0.433 1.494 -0.337 0.631 0.064
YWHAG 0 0.298 -0.025
YWHAG 0 1.488 0.233 0.098
BCL2L1 0
CEBPB 0 0.400 -0.930
STAT5B 0 0.670 -0.960
GRB2 0 -0.240 0.300 -1.021 0.057 0.906
PTPN11 0 -0.210 -0.400 0.644 1.053 0.451

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BCL2L1 Ubiquitylation K87 0.026 _EVIPMAAVK(gl)QALR_
CEBPB Phosphorylation S231 -0.660 _AYLGYQAVPSGSSGSLSTSSSSS(ph)PPGTPSPADAK_
GRB2 Ubiquitylation K10 0.146 _YDFK(gl)ATADDELSFK_
GRB2 Ubiquitylation K20 -0.078 _ATADDELSFK(gl)R_
GRB2 Ubiquitylation K69 -0.362 0.641 _AK(gl)AEEMLSK_
GRB2 Ubiquitylation K76 0.754 _AEEMLSK(gl)QR_
GRB2 Ubiquitylation K109 0.381 -0.002 _FGNDVQHFK(gl)VLR_
HDAC1 Ubiquitylation K50 0.036 _K(gl)MEIYRPHK_
HDAC1 Ubiquitylation K66 -0.593 _ANAEEMTK(gl)YHSDDYIK_
HDAC1 Ubiquitylation K74 0.620 -1.473 _YHSDDYIK(gl)FLR_
HDAC1 Ubiquitylation K89 0.749 -0.241 _SIRPDNMSEYSK(gl)QMQR_
HDAC1 Phosphorylation S393 -1.133 -1.144 _M(ox)LPHAPGVQM(ox)QAIPEDAIPEES(ph)GDEDEDDPDKR_
HDAC1 Phosphorylation S409 1.326 1.144 _ISICS(ph)SDKR_
HDAC1 Phosphorylation S410 1.326 1.144 _ISICS(ph)SDKR_
HDAC1 Ubiquitylation K412 0.642 -0.744 _ISICSSDK(gl)R_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
PRKACA Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACA Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
PTPN11 Ubiquitylation K124 0.562 _EAEK(gl)LLTEK_
SRP9 Ubiquitylation K16 -0.609 _AAEK(gl)LYLADPMK(gl)AR_
SRP9 Ubiquitylation K24 1.005 -0.026 _LYLADPM(ox)K(gl)AR_
SRP9 Ubiquitylation K52 -0.183 _VTDDLVCLVYK(gl)TDQAQDVK_
SRP9 Ubiquitylation K60 -0.106 _TDQAQDVK(gl)K(gl)IEK_
SRP9 Ubiquitylation K61 -1.045 _TDQAQDVK(gl)K(gl)IEK_
SRP9 Ubiquitylation K64 0.432 _IEK(gl)FHSQLMR_
SRP9 Ubiquitylation K76 0.236 0.603 _LM(ox)VAK(gl)EAR_
STAT5B Phosphorylation S194 0.270 _IQAQFGPLAQLS(ph)PQER_
YWHAG Ubiquitylation K10 1.000 1.070 _VDREQLVQK(gl)AR_
YWHAG Ubiquitylation K69 0.708 1.242 _VISSIEQK(gl)TSADGNEK_
YWHAG Ubiquitylation K120 1.386 _NCSETQYESK(gl)VFYLK_
YWHAG Ubiquitylation K125 0.512 0.946 _VFYLK(gl)MK_
YWHAG Ubiquitylation K142 0.456 0.610 _YLAEVATGEK(gl)R_
YWHAZ Ubiquitylation K3 0.268 0.388 _(ac)MDK(gl)NELVQK_
YWHAZ Ubiquitylation K9 0.917 0.954 _(ac)MDKNELVQK(gl)AK_
YWHAZ Ubiquitylation K11 0.016 0.388 _AK(gl)LAEQAERYDDMAACMK_
YWHAZ Ubiquitylation K49 0.656 1.019 _NLLSVAYK(gl)NVVGAR_
YWHAZ Ubiquitylation K68 0.504 _VVSSIEQK(gl)TEGAEK_
YWHAZ Ubiquitylation K74 0.762 _VVSSIEQKTEGAEK(gl)K_
YWHAZ Ubiquitylation K85 -0.089 _EK(gl)IETELR_
YWHAZ Ubiquitylation K122 0.498 0.837 _MK(gl)GDYYR_
YWHAZ Ubiquitylation K138 0.560 1.003 _YLAEVAAGDDK(gl)K_
YWHAZ Ubiquitylation K139 0.551 1.003 _YLAEVAAGDDKK(gl)_
YWHAZ Ubiquitylation K166 -0.439 -0.371 _K(gl)EMQPTHPIR_


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