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Query: SRP9

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRP9 0 1.812 -0.690 0.840 -0.559 -0.644 0.111 -0.103

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRP9 Ubiquitylation K76 0.236 0.603 _LM(ox)VAK(gl)EAR_
SRP9 Ubiquitylation K24 1.005 -0.026 _LYLADPM(ox)K(gl)AR_
SRP9 Ubiquitylation K16 -0.609 _AAEK(gl)LYLADPMK(gl)AR_
SRP9 Ubiquitylation K52 -0.183 _VTDDLVCLVYK(gl)TDQAQDVK_
SRP9 Ubiquitylation K60 -0.106 _TDQAQDVK(gl)K(gl)IEK_
SRP9 Ubiquitylation K61 -1.045 _TDQAQDVK(gl)K(gl)IEK_
SRP9 Ubiquitylation K64 0.432 _IEK(gl)FHSQLMR_

Background Information for SRP9:


Pubmed-SRP9 »
Uniprot-SRP9 »
Biogrid-SRP9 »
ProteomicsDB-SRP9 »

Tumorportal-SRP9 »
COSMIC-SRP9 »
GenomeRNAi-SRP9 »
Genecards-SRP9


Protein-protein Interactions for SRP9
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EDC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC1;RP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SRP9
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Signal_recog_particle_SRP9/14 IPR009018 0.17


Protein complexes (CORUM database) featuring SRP9
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SRP9
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members Pathway Pathway_914 KEGG_PROTEIN_EXPORT 0 0.7
Category members GO Category GO:0048500 signal recognition particle Database 0.62
Category members GO Category GO:0005786 signal recognition particle, endoplasmic reticulum targeting Database 0.46
Category members GO Category GO:0008312 7S RNA binding Database 0.31
Category members Pathway Pathway_550 PID_IL3_PATHWAY 0 0
Category members GO Category GO:0005047 signal recognition particle binding Database 0
Category members GO Category GO:0005785 signal recognition particle receptor complex Database 0
Category members GO Category GO:0045900 negative regulation of translational elongation Database 0


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