RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
GSK3B	2	1.020	-0.870				-1.128	1.091
EPB41L1	2	-0.670	1.160	0.965	-0.443	-0.532	0.843	0.638
EPB41L1	2	-0.670	1.160	-0.401
FOXO3	2	-0.410	-0.120
YWHAE	1	0.440	-0.380		1.095	-0.160
YWHAE	1	0.440	-0.380	1.129			0.621	0.321
CCND1	1	-1.820	3.470
PLCG1	1	-0.170	0.000
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
YWHAQ	1	-0.260	0.670	0.606	0.369	-0.163	0.594	0.478
NRAS	1	1.810	-0.720				0.246	-0.346
BAD	0	-0.660	1.190
CAMK2A	0	-0.430	0.130		-0.654	0.073
CAMK2A	0	-0.430	0.130	-0.619			0.544	0.125
GAB1	0	1.950	-1.110
SOS1	0	0.500	-0.620	-0.570
CREB1	0	1.080	-0.800			-1.027
PIK3CA	0
YWHAH	0	0.000	0.080		1.206	0.159
YWHAH	0	0.000	0.080	0.546			0.338	0.541
PDPK1	0	0.050	-0.440
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
PIK3R1	0	1.910	-1.220				-0.441	0.147
CAMK4	0	0.780	-0.790
PRKCD	0	0.250	0.070				0.578	0.427
YWHAZ	0	0.880	-0.450	0.433	1.494	-0.337	0.631	0.064
YWHAB	0				0.628	-0.543
YWHAB	0			0.507			0.271	0.503
YWHAG	0				0.298	-0.025
YWHAG	0			1.488			0.233	0.098
HRAS	0	1.470	-0.520
SFN	0	0.890	0.120				-4.300
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
SRC	0	0.050	0.470	-0.031

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
BAD	Phosphorylation	S74	-0.904	-0.452	_HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD	Phosphorylation	S75	-0.914	-0.660	_HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD	Phosphorylation	S97		0.056	_S(ph)RSAPPNLWAAQR_
BAD	Phosphorylation	S99	-0.299	0.161	_S(ph)APPNLWAAQR_
BAD	Phosphorylation	S118	1.277	1.089	_RM(ox)S(ph)DEFVDSFKK_
CAMK2A	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK4	Phosphorylation	S360	-0.256	0.086	_DPS(ph)PIQDGNEDMK_
CCND1	Ubiquitylation	K33		-0.490	_AMLK(gl)AEETCAPSVSYFK_
CCND1	Ubiquitylation	K46	-1.016	-0.036	_AEETCAPSVSYFK(gl)CVQK_
CCND1	Ubiquitylation	K95	-0.733	-0.137	_FLSLEPVK(gl)K_
CCND1	Ubiquitylation	K96	-0.846	-0.155	_FLSLEPVKK(gl)_
CCND1	Ubiquitylation	K238		0.245	_VIK(gl)CDPDCLR_
CREB1	Phosphorylation	S271	-0.979	-1.450	_TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1	Ubiquitylation	K333	1.343		_ALK(gl)DLYCHK_
EPB41L1	Phosphorylation	S95	2.058	1.653	_SQVS(ph)EEEGKEVESDKEK_
EPB41L1	Phosphorylation	S188	0.343	0.603	_IEVKEES(ph)PQSK_
EPB41L1	Phosphorylation	S191		0.304	_IEVKEESPQS(ph)K_
EPB41L1	Ubiquitylation	K198	0.148		_AETELK(gl)ASQKPIRK_
EPB41L1	Ubiquitylation	K237	1.265	1.069	_GQDLLK(gl)R_
EPB41L1	Ubiquitylation	K361	0.451		_LAPNQTK(gl)ELEEK_
EPB41L1	Ubiquitylation	K366	0.532		_ELEEK(gl)VMELHK_
EPB41L1	Ubiquitylation	K372	0.922		_VMELHK(gl)SYR_
EPB41L1	Phosphorylation	T475	0.990	1.178	_SEAEEGEVRT(ph)PTK_
EPB41L1	Ubiquitylation	K499	-0.476		_SK(gl)FLALGSK_
EPB41L1	Phosphorylation	S510		0.594	_HQAS(ph)INELKR_
EPB41L1	Phosphorylation	S542	0.751	0.712	_S(ph)LDGAAAVDSADR_
EPB41L1	Phosphorylation	S544	-0.490	-0.553	_RLPSSPAS(ph)PSPK_
EPB41L1	Phosphorylation	S551	-0.139		_SLDGAAAVDS(ph)ADRSPRPTSAPAITQGQVAEGGVLDASAK_
EPB41L1	Phosphorylation	S555	-0.200	-1.109	_SLDGAAAVDSADRS(ph)PRPTSAPAITQGQVAEGGVLDASAK_
EPB41L1	Phosphorylation	S560	-0.232	0.037	_SPRPTS(ph)APAITQGQVAEGGVLDASAK_
EPB41L1	Phosphorylation	S709		0.307	_RLS(ph)THSPFR_
EPB41L1	Phosphorylation	S712	-0.493	0.130	_LSTHS(ph)PFR_
EPB41L1	Phosphorylation	S784	0.234	0.250	_SLS(ph)PIIGK_
FOXO3	Phosphorylation	S12		-1.324	_(ac)AEAPASPAPLS(ph)PLEVELDPEFEPQSRPR_
FOXO3	Phosphorylation	S253		2.510	_AVS(ph)MDNSNKYTK_
FOXO3	Phosphorylation	S284	4.138	6.011	_AALQTAPESADDS(ph)PSQLSK_
FOXO3	Phosphorylation	S421		1.295	_GS(ph)GLGSPTSSFNSTVFGPSSLNSLR_
FOXO3	Phosphorylation	S425		1.471	_GSGLGS(ph)PTSSFNSTVFGPSSLNSLR_
GAB1	Phosphorylation	S266	0.756	0.551	_SYS(ph)HDVLPK_
GAB1	Phosphorylation	S367	0.230	0.176	_TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	T369		-0.352	_TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	S381	-0.481	0.139	_TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1	Phosphorylation	S401	0.266	0.788	_DAS(ph)SQDCYDIPR_
GAB1	Phosphorylation	S402	0.328	0.633	_DASS(ph)QDCYDIPR_
GAB1	Phosphorylation	S419		0.540	_SSS(ph)LEGFHNHFK_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
GSK3B	Phosphorylation	S9	-0.483	0.010	_TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B	Ubiquitylation	K85		-0.204	_LCDSGELVAIK(gl)K_
GSK3B	Ubiquitylation	K86		-0.204	_LCDSGELVAIK(gl)K_
GSK3B	Phosphorylation	S215	0.296	0.477	_GEPNVS(ph)YICSR_
GSK3B	Phosphorylation	Y216	0.356	0.376	_GEPNVSY(ph)ICSR_
GSK3B	Phosphorylation	T390	2.800	2.527	_IQAAAST(ph)PTNATAASDANTGDR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PDPK1	Phosphorylation	S241	0.358	0.361	_ANS(ph)FVGTAQYVSPELLTEK_
PDPK1	Ubiquitylation	K257	0.571	-0.234	_ANSFVGTAQYVSPELLTEK(gl)SACK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PLCG1	Ubiquitylation	K300		8.031	_DLK(gl)NMLSQVNYR_
PLCG1	Ubiquitylation	K348		-0.219	_SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1	Ubiquitylation	K552		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K553		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K1063	0.864	0.355	_LTEGK(gl)IMER_
PLCG1	Phosphorylation	S1370	0.475	0.515	_AREGS(ph)FESR_
PRKCD	Ubiquitylation	K138	-0.141		_SEDEAK(gl)FPTMNR_
PRKCD	Ubiquitylation	K222	0.185	0.658	_DTIFQK(gl)ER_
PRKCD	Phosphorylation	S302	-0.240	-0.222	_S(ph)DSASSEPVGIYQGFEK_
PRKCD	Phosphorylation	S304	0.378	0.289	_RSDS(ph)ASSEPVGIYQGFEK_
PRKCD	Phosphorylation	S506	-0.213	0.200	_AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD	Phosphorylation	T507	-0.149	0.240	_AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD	Ubiquitylation	K641	-2.000		_DYSNFDQEFLNEK(gl)AR_
PRKCD	Phosphorylation	S645	0.577	0.832	_ARLS(ph)YSDK_
PRKCD	Phosphorylation	S647	0.886	0.853	_ARLSYS(ph)DK_
SFN	Ubiquitylation	K11	0.561	0.388	_AK(gl)LAEQAER_
SFN	Ubiquitylation	K49	-0.093	0.337	_NLLSVAYK(gl)_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
YWHAB	Ubiquitylation	K11	1.057	1.322	_(ac)TMDKSELVQK(gl)AK_
YWHAB	Ubiquitylation	K13	0.060	0.388	_AK(gl)LAEQAER_
YWHAB	Ubiquitylation	K70	0.558	-0.175	_VISSIEQK(gl)TER_
YWHAB	Ubiquitylation	K140		0.531	_YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB	Ubiquitylation	K159	0.300		_QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB	Ubiquitylation	K160	-0.439	-0.371	_K(gl)EMQPTHPIR_
YWHAE	Ubiquitylation	K38	0.710	1.822	_YDEMVESMK(gl)K_
YWHAE	Ubiquitylation	K39		1.734	_YDEMVESMKK(gl)_
YWHAE	Ubiquitylation	K60	0.554	1.732	_NLLSVAYK(gl)NVIGAR_
YWHAE	Ubiquitylation	K83	0.375	0.643	_IISSIEQKEENK(gl)GGEDKLK_
YWHAE	Ubiquitylation	K90	1.103		_GGEDKLK(gl)MIR_
YWHAE	Ubiquitylation	K116	-0.289		_LICCDILDVLDK(gl)HLIPAANTGESK_
YWHAE	Ubiquitylation	K133	0.653	1.264	_VFYYK(gl)M(ox)K_
YWHAE	Ubiquitylation	K152	0.031	0.601	_K(gl)EAAENSLVAYK_
YWHAE	Phosphorylation	S210	0.534	0.506	_AAFDDAIAELDTLS(ph)EESYK_
YWHAE	Phosphorylation	S213		0.541	_AAFDDAIAELDTLSEES(ph)YK_
YWHAG	Ubiquitylation	K10	1.000	1.070	_VDREQLVQK(gl)AR_
YWHAG	Ubiquitylation	K69	0.708	1.242	_VISSIEQK(gl)TSADGNEK_
YWHAG	Ubiquitylation	K120		1.386	_NCSETQYESK(gl)VFYLK_
YWHAG	Ubiquitylation	K125	0.512	0.946	_VFYLK(gl)MK_
YWHAG	Ubiquitylation	K142	0.456	0.610	_YLAEVATGEK(gl)R_
YWHAH	Ubiquitylation	K143	0.540		_YLAEVASGEKK(gl)_
YWHAQ	Ubiquitylation	K3		0.827	_(ac)MEK(gl)TELIQK_
YWHAQ	Ubiquitylation	K9	0.588	0.253	_(ac)MEKTELIQK(gl)AK_
YWHAQ	Ubiquitylation	K11	0.561	0.388	_AK(gl)LAEQAER_
YWHAQ	Ubiquitylation	K27	-0.849		_YDDMATCMK(gl)AVTEQGAELSNEER_
YWHAQ	Ubiquitylation	K49	0.260	0.469	_NLLSVAYK(gl)NVVGGR_
YWHAQ	Ubiquitylation	K68	0.288		_VISSIEQK(gl)TDTSDKK_
YWHAQ	Ubiquitylation	K74	0.305		_TDTSDK(gl)KLQLIK_
YWHAQ	Ubiquitylation	K75	0.253		_TDTSDKK(gl)LQLIK_
YWHAQ	Ubiquitylation	K80	0.655	1.500	_LQLIK(gl)DYR_
YWHAQ	Ubiquitylation	K85	0.110		_EK(gl)VESELR_
YWHAQ	Ubiquitylation	K120	0.512	0.946	_VFYLK(gl)MK_
YWHAQ	Ubiquitylation	K122	0.426	0.859	_MK(gl)GDYFR_
YWHAQ	Ubiquitylation	K158	-0.439	-0.371	_K(gl)EMQPTHPIR_
YWHAZ	Ubiquitylation	K3	0.268	0.388	_(ac)MDK(gl)NELVQK_
YWHAZ	Ubiquitylation	K9	0.917	0.954	_(ac)MDKNELVQK(gl)AK_
YWHAZ	Ubiquitylation	K11	0.016	0.388	_AK(gl)LAEQAERYDDMAACMK_
YWHAZ	Ubiquitylation	K49	0.656	1.019	_NLLSVAYK(gl)NVVGAR_
YWHAZ	Ubiquitylation	K68	0.504		_VVSSIEQK(gl)TEGAEK_
YWHAZ	Ubiquitylation	K74	0.762		_VVSSIEQKTEGAEK(gl)K_
YWHAZ	Ubiquitylation	K85	-0.089		_EK(gl)IETELR_
YWHAZ	Ubiquitylation	K122	0.498	0.837	_MK(gl)GDYYR_
YWHAZ	Ubiquitylation	K138	0.560	1.003	_YLAEVAAGDDK(gl)K_
YWHAZ	Ubiquitylation	K139	0.551	1.003	_YLAEVAAGDDKK(gl)_
YWHAZ	Ubiquitylation	K166	-0.439	-0.371	_K(gl)EMQPTHPIR_