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Query: EPB41L1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EPB41L1 2 8.677 -0.670 1.160 -0.401
EPB41L1 2 8.677 -0.670 1.160 0.965 -0.443 -0.532 0.843 0.638

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EPB41L1 Phosphorylation S95 2.058 1.653 _SQVS(ph)EEEGKEVESDKEK_
EPB41L1 Phosphorylation T475 0.990 1.178 _SEAEEGEVRT(ph)PTK_
EPB41L1 Ubiquitylation K237 1.265 1.069 _GQDLLK(gl)R_
EPB41L1 Phosphorylation S542 0.751 0.712 _S(ph)LDGAAAVDSADR_
EPB41L1 Phosphorylation S188 0.343 0.603 _IEVKEES(ph)PQSK_
EPB41L1 Phosphorylation S510 0.594 _HQAS(ph)INELKR_
EPB41L1 Phosphorylation S709 0.307 _RLS(ph)THSPFR_
EPB41L1 Phosphorylation S191 0.304 _IEVKEESPQS(ph)K_
EPB41L1 Phosphorylation S784 0.234 0.250 _SLS(ph)PIIGK_
EPB41L1 Phosphorylation S712 -0.493 0.130 _LSTHS(ph)PFR_
EPB41L1 Phosphorylation S560 -0.232 0.037 _SPRPTS(ph)APAITQGQVAEGGVLDASAK_
EPB41L1 Phosphorylation S544 -0.490 -0.553 _RLPSSPAS(ph)PSPK_
EPB41L1 Phosphorylation S555 -0.200 -1.109 _SLDGAAAVDSADRS(ph)PRPTSAPAITQGQVAEGGVLDASAK_
EPB41L1 Ubiquitylation K198 0.148 _AETELK(gl)ASQKPIRK_
EPB41L1 Ubiquitylation K361 0.451 _LAPNQTK(gl)ELEEK_
EPB41L1 Ubiquitylation K366 0.532 _ELEEK(gl)VMELHK_
EPB41L1 Ubiquitylation K372 0.922 _VMELHK(gl)SYR_
EPB41L1 Ubiquitylation K499 -0.476 _SK(gl)FLALGSK_
EPB41L1 Phosphorylation S551 -0.139 _SLDGAAAVDS(ph)ADRSPRPTSAPAITQGQVAEGGVLDASAK_

Background Information for EPB41L1:


Pubmed-EPB41L1 »
Uniprot-EPB41L1 »
Biogrid-EPB41L1 »
ProteomicsDB-EPB41L1 »

Tumorportal-EPB41L1 »
COSMIC-EPB41L1 »
GenomeRNAi-EPB41L1 »
Genecards-EPB41L1


Protein-protein Interactions for EPB41L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRD2;DKFZp313H139 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARMC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf104 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDAH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGUOK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3I Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISG20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRICKLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EPB41L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members SAB_dom IPR007477 1.02
Category members Band_4.1_C IPR008379 1.02
Category members Band_41_protein IPR021187 1.02
Category members Ez/rad/moesin_like IPR000798 0.38
Category members FERM_N IPR018979 0.36
Category members FERM_PH-like_C IPR018980 0.35
Category members Band_41_fam IPR019750 0.33
Category members FERM-adjacent IPR014847 0.08
Category members FERM_domain IPR000299 0
Category members FERM_central IPR019748 0
Category members Band_41_domain IPR019749 0


Protein complexes (CORUM database) featuring EPB41L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EPB41L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members Pathway Pathway_636 PID_PI3K_PLC_TRK_PATHWAY 0 1.85
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0030866 cortical actin cytoskeleton organization Database 0.89
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members Pathway Pathway_1011 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS 0 0.18
Category members Disease phenotype Autosomal_dominant_non-syndromic_intellectual_disability Autosomal dominant non-syndromic intellectual disability Database 0.08
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_230 REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 0 0
Category members GO Category GO:0019898 extrinsic to membrane Database 0


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