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Query: GIT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GIT1 0 1.181 0.720 -0.330 -1.751 0.439

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GIT1 Phosphorylation S374 1.018 1.475 _SLS(ph)SPTDNLELSLR_
GIT1 Phosphorylation S375 0.909 1.262 _SLSS(ph)PTDNLELSLR_
GIT1 Phosphorylation S401 0.624 0.935 _SQSDLDDQHDYDSVAS(ph)DEDTDQEPLR_
GIT1 Phosphorylation S423 0.332 0.924 _ARS(ph)MDSSDLSDGAVTLQEYLELKK_
GIT1 Phosphorylation S605 0.173 0.037 _HGS(ph)GADSDYENTQSGDPLLGLEGK_

Background Information for GIT1:


Pubmed-GIT1 »
Uniprot-GIT1 »
Biogrid-GIT1 »
ProteomicsDB-GIT1 »

Tumorportal-GIT1 »
COSMIC-GIT1 »
GenomeRNAi-GIT1 »
Genecards-GIT1


Protein-protein Interactions for GIT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PAK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLC33A1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARHGEF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARHGEF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CROCC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GIT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ICAM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAFF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCKIPSD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RABGGTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYNC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GIT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ArfGAP IPR001164 0
Category members Ankyrin_rpt IPR002110 0
Category members GIT_SHD IPR013724 0
Category members Ankyrin_rpt-contain_dom IPR020683 0
Category members GIT1_C IPR022018 0


Protein complexes (CORUM database) featuring GIT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 930 Scrib-beta-PIX-GIT1 complex Database 0.32
Category members Corum 1810 ITGA4-PXN-GIT1 complex Database 0.25


Categories featuring GIT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_466 PID_ECADHERIN_STABILIZATION_PATHWAY 0 1.4
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members Pathway Pathway_992 PID_ARF6_PATHWAY 0 0.46
Category members Pathway Pathway_985 PID_AURORA_A_PATHWAY 0 0.34
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members Pathway Pathway_188 KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 0 0.24
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members Pathway Pathway_293 PID_CDC42_REG_PATHWAY 0 0.05
Category members Pathway Pathway_1024 PID_INTEGRIN_A4B1_PATHWAY 0 0
Category members GO Category GO:0008060 ARF GTPase activator activity Database 0
Category members GO Category GO:0008277 regulation of G-protein coupled receptor protein signaling pathway Database 0
Category members GO Category GO:0032312 regulation of ARF GTPase activity Database 0


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