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Query: TBP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TBP 0 -1.548 1.610 -1.170 -0.831

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TBP Ubiquitylation K181 -0.140 -0.577 _LDLK(gl)TIALR_
TBP Ubiquitylation K225 -0.596 _MVCTGAK(gl)SEEQSR_

Background Information for TBP:


Pubmed-TBP »
Uniprot-TBP »
Biogrid-TBP »
ProteomicsDB-TBP »

Tumorportal-TBP »
COSMIC-TBP »
GenomeRNAi-TBP »
Genecards-TBP


Protein-protein Interactions for TBP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CUEDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NFKBIB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TBP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TBP IPR000814 0.29


Protein complexes (CORUM database) featuring TBP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1257 ALL-1 supercomplex Database 4.3
Category members Corum 2825 BRCA1-RNA polymerase II complex Database 1.38
Category members Corum 103 RNA polymerase II holoenzyme complex Database 1.07
Category members Corum 3064 RNA polymerase II complex, chromatin structure modifying Database 0.64
Category members Corum 1114 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex Database 0.25
Category members Corum 5727 TBP-TAF complex Database 0.13
Category members Corum 1321 Transcription initiation factor complex (TAF5, TAF6, TAF9, TAF11, TBP) Database 0.05
Category members Corum 493 DAB complex Database 0.04
Category members Corum 1318 Transcription initiation factor complex (TAF1, TAF5, TAF11, TAF12, TBP) Database 0
Category members Corum 155 TFIID complex Database 0
Category members Corum 1749 SMN-PolII-RHA complex Database 0
Category members Corum 3009 TFIID complex Database 0
Category members Corum 463 TFIID-beta complex Database 0
Category members Corum 469 TFIID-beta complex Database 0
Category members Corum 484 TFIID complex Database 0
Category members Corum 485 TFIID complex, B-cell specific Database 0
Category members Corum 492 DA complex Database 0
Category members Corum 508 TFIID complex Database 0
Category members Corum 509 TFIID complex Database 0
Category members Corum 514 TFIID-beta complex Database 0
Category members Corum 5736 Pre-initiation complex (PIC) Database 0


Categories featuring TBP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0006352 DNA-dependent transcription, initiation Database 3.76
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members Pathway Pathway_355 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER 0 0.37
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0001103 RNA polymerase II repressing transcription factor binding Database 0.36
Category members Pathway Pathway_370 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING 0 0.34
Category members Pathway Pathway_45 PID_REG_GR_PATHWAY 0 0.31
Category members Pathway Pathway_357 REACTOME_RNA_POL_III_TRANSCRIPTION 0 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0045120 pronucleus Database 0.27
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_406 PID_RB_1PATHWAY 0 0.21
Category members Pathway Pathway_142 PID_MYC_REPRESS_PATHWAY 0 0.21
Category members GO Category GO:0006383 transcription from RNA polymerase III promoter Database 0.18
Category members GO Category GO:0005719 nuclear euchromatin Database 0.15
Category members Pathway Pathway_352 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER 0 0.11
Category members Pathway Pathway_381 BIOCARTA_RARRXR_PATHWAY 0 0.08
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_365 BIOCARTA_CARM_ER_PATHWAY 0 0
Category members Pathway Pathway_856 KEGG_BASAL_TRANSCRIPTION_FACTORS 0 0
Category members GO Category GO:0001939 female pronucleus Database 0
Category members GO Category GO:0001940 male pronucleus Database 0
Category members GO Category GO:0005669 transcription factor TFIID complex Database 0
Category members GO Category GO:0005672 transcription factor TFIIA complex Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0070491 repressing transcription factor binding Database 0


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