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Query: NOC2L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NOC2L 1 4.712 1.010 -0.760
NOC2L 1 4.712 1.010 -0.760 -0.322 0.179 0.516 0.566 0.288

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NOC2L Ubiquitylation K144 2.425 _K(gl)NSVPVTVAMVER_
NOC2L Phosphorylation S672 0.375 0.458 _DLFDLNS(ph)SEEDDTEGFSER_
NOC2L Phosphorylation S673 0.408 0.312 _DLFDLNSS(ph)EEDDTEGFSER_
NOC2L Ubiquitylation K516 -0.170 _LSNVNLQEK(gl)AYR_
NOC2L Ubiquitylation K226 -0.886 -0.310 _LLFGK(gl)VAK_
NOC2L Ubiquitylation K649 -1.048 -0.355 _LEDLNFPEIK(gl)R_
NOC2L Phosphorylation S49 -0.694 -0.494 _EAARS(ph)PDKPGGSPSASR_
NOC2L Ubiquitylation K562 -0.563 _ECK(gl)VANYCR_
NOC2L Phosphorylation S56 -1.635 -0.706 _SPDKPGGS(ph)PSASRR_
NOC2L Ubiquitylation K245 -1.994 _MLQPSSSPLWGK(gl)LR_
NOC2L Ubiquitylation K576 -1.085 _QVQQLLGK(gl)VQENSAYICSR_
NOC2L Ubiquitylation K637 0.193 _EIQLEISGK(gl)ER_

Background Information for NOC2L:


Pubmed-NOC2L »
Uniprot-NOC2L »
Biogrid-NOC2L »
ProteomicsDB-NOC2L »

Tumorportal-NOC2L »
COSMIC-NOC2L »
GenomeRNAi-NOC2L »
Genecards-NOC2L


Protein-protein Interactions for NOC2L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EED Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait CPNE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEB10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDGFB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRP8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF512 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NOC2L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring NOC2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NOC2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042393 histone binding Database 0.94
Category members Pathway Pathway_208 PID_TAP63_PATHWAY 0 0.52
Category members GO Category GO:0034644 cellular response to UV Database 0.49
Category members GO Category GO:0031491 nucleosome binding Database 0.24
Category members GO Category GO:0032066 nucleolus to nucleoplasm transport Database 0.11
Category members GO Category GO:0035067 negative regulation of histone acetylation Database 0.08
Category members GO Category GO:0031497 chromatin assembly Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0002903 negative regulation of B cell apoptotic process Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0070491 repressing transcription factor binding Database 0


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