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Query: HDAC7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HDAC7 0 1.271 -0.840 1.260

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HDAC7 Phosphorylation S181 -0.436 0.447 _KES(ph)APPSLR_
HDAC7 Phosphorylation S486 -0.969 -0.754 _AQS(ph)SPAAPASLSAPEPASQAR_

Background Information for HDAC7:


Pubmed-HDAC7 »
Uniprot-HDAC7 »
Biogrid-HDAC7 »
ProteomicsDB-HDAC7 »

Tumorportal-HDAC7 »
COSMIC-HDAC7 »
GenomeRNAi-HDAC7 »
Genecards-HDAC7


Protein-protein Interactions for HDAC7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait YWHAH Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HDAC7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members His_deacetylse IPR000286 0
Category members Histone_deAcase_II_euk IPR017320 0
Category members His_deacetylse_dom IPR023801 0


Protein complexes (CORUM database) featuring HDAC7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3 BCL6-HDAC7 complex Database 0


Categories featuring HDAC7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_308 PID_AR_TF_PATHWAY 0 0.86
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members GO Category GO:0007043 cell-cell junction assembly Database 0.31
Category members Pathway Pathway_1143 PID_HDAC_CLASSII_PATHWAY 0 0.3
Category members GO Category GO:0045668 negative regulation of osteoblast differentiation Database 0.29
Category members Pathway Pathway_789 REACTOME_SIGNALING_BY_NOTCH1 0 0.22
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members Pathway Pathway_824 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 0 0.14
Category members Pathway Pathway_52 PID_HIF1_TFPATHWAY 0 0.11
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0005080 protein kinase C binding Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_365 BIOCARTA_CARM_ER_PATHWAY 0 0
Category members GO Category GO:0000118 histone deacetylase complex Database 0
Category members GO Category GO:0001570 vasculogenesis Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0004407 histone deacetylase activity Database 0
Category members GO Category GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) Database 0
Category members GO Category GO:0032703 negative regulation of interleukin-2 production Database 0
Category members GO Category GO:0033613 activating transcription factor binding Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific) Database 0
Category members GO Category GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific) Database 0
Category members GO Category GO:0070491 repressing transcription factor binding Database 0


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