Results for the Category
NAD-dependent histone deacetylase activity (H3-K14 specific)
(GO:0032041)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| HDAC9 | 1 | -1.710 | 3.420 | |||||
| HDAC1 | 1 | -1.980 | 4.450 | |||||
| HDAC1 | 1 | -1.980 | 4.450 | -0.122 | 0.307 | 0.969 | 0.094 | 0.191 |
| HDAC2 | 1 | -2.390 | 4.970 | |||||
| HDAC2 | 1 | -2.390 | 4.970 | 0.187 | -0.007 | 0.825 | ||
| HDAC7 | 0 | -0.840 | 1.260 | |||||
| HDAC4 | 0 | 1.730 | -0.740 | |||||
| HDAC5 | 0 | -0.830 | 1.270 | |||||
| HDAC11 | 0 | -1.480 | 2.420 | |||||
| HDAC11 | 0 | -1.480 | 2.420 | |||||
| HDAC3 | 0 | -0.790 | 1.070 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| HDAC1 | Ubiquitylation | K50 | 0.036 | _K(gl)MEIYRPHK_ | |
| HDAC1 | Ubiquitylation | K66 | -0.593 | _ANAEEMTK(gl)YHSDDYIK_ | |
| HDAC1 | Ubiquitylation | K74 | 0.620 | -1.473 | _YHSDDYIK(gl)FLR_ |
| HDAC1 | Ubiquitylation | K89 | 0.749 | -0.241 | _SIRPDNMSEYSK(gl)QMQR_ |
| HDAC1 | Phosphorylation | S393 | -1.133 | -1.144 | _M(ox)LPHAPGVQM(ox)QAIPEDAIPEES(ph)GDEDEDDPDKR_ |
| HDAC1 | Phosphorylation | S409 | 1.326 | 1.144 | _ISICS(ph)SDKR_ |
| HDAC1 | Phosphorylation | S410 | 1.326 | 1.144 | _ISICS(ph)SDKR_ |
| HDAC1 | Ubiquitylation | K412 | 0.642 | -0.744 | _ISICSSDK(gl)R_ |
| HDAC11 | Ubiquitylation | K50 | 1.042 | _VINFLK(gl)EEK_ | |
| HDAC11 | Phosphorylation | S121 | -0.871 | -0.105 | _SPSS(ph)FCLSVWR_ |
| HDAC2 | Ubiquitylation | K50 | 0.036 | _K(gl)MEIYRPHK_ | |
| HDAC2 | Ubiquitylation | K67 | -0.467 | _ATAEEMTK(gl)YHSDEYIK_ | |
| HDAC2 | Ubiquitylation | K89 | 0.749 | -0.241 | _SIRPDNMSEYSK(gl)QMQR_ |
| HDAC2 | Ubiquitylation | K284 | 0.749 | _GHAK(gl)CVEVVK_ | |
| HDAC2 | Phosphorylation | S394 | -0.865 | -0.997 | _M(ox)LPHAPGVQM(ox)QAIPEDAVHEDS(ph)GDEDGEDPDKR_ |
| HDAC2 | Phosphorylation | S422 | 0.482 | 0.781 | _IACDEEFS(ph)DSEDEGEGGR_ |
| HDAC3 | Phosphorylation | S424 | -0.354 | _GPEENYSRPEAPNEFYDGDHDNDKES(ph)DVEI_ | |
| HDAC4 | Phosphorylation | S265 | -0.390 | _RS(ph)SPLLR_ | |
| HDAC4 | Phosphorylation | S266 | -0.821 | -0.598 | _RSS(ph)PLLR_ |
| HDAC4 | Phosphorylation | S632 | -1.146 | -0.837 | _AQS(ph)SPASATFPVSVQEPPTKPR_ |
| HDAC5 | Phosphorylation | S265 | -0.390 | _RS(ph)SPLLR_ | |
| HDAC5 | Phosphorylation | S266 | -0.821 | -0.598 | _RSS(ph)PLLR_ |
| HDAC7 | Phosphorylation | S181 | -0.436 | 0.447 | _KES(ph)APPSLR_ |
| HDAC7 | Phosphorylation | S486 | -0.969 | -0.754 | _AQS(ph)SPAAPASLSAPEPASQAR_ |
| HDAC9 | Phosphorylation | S265 | -0.390 | _RS(ph)SPLLR_ | |
| HDAC9 | Phosphorylation | S266 | -0.821 | -0.598 | _RSS(ph)PLLR_ |
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