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Query: ZMYND8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZMYND8 0 3.664 1.480 -1.040
ZMYND8 0 3.664 1.480 -1.040 -0.721 -0.104
ZMYND8 0 3.664 1.480 -1.040 0.151 1.057 1.056 0.009
ZMYND8 0 3.664 1.480 -1.040 -0.793 0.183 0.741 0.799 0.587

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZMYND8 Phosphorylation S433 0.711 0.935 _LNFDMTAS(ph)PK_
ZMYND8 Phosphorylation S487 0.758 0.909 _KATSSHFS(ph)ASEESM(ox)DFLDK_
ZMYND8 Phosphorylation S452 1.424 0.458 _RIS(ph)LSDMPR_
ZMYND8 Phosphorylation S764 0.454 _EPS(ph)PKQDVVGK_
ZMYND8 Phosphorylation S695 0.298 0.206 _DKAS(ph)PEPEKDFSEK_
ZMYND8 Phosphorylation S574 -0.130 0.057 _ELSESVQQQSTPVPLIS(ph)PKR_
ZMYND8 Phosphorylation S517 -0.203 -0.342 _TGQAGSLSGS(ph)PKPFSPQLSAPITTK_
ZMYND8 Phosphorylation S783 -0.726 -0.795 _TPPSTTVGSHS(ph)PPETPVLTR_
ZMYND8 Phosphorylation S515 -0.248 _TGQAGSLS(ph)GSPKPFSPQLSAPITTK_
ZMYND8 Ubiquitylation K535 -0.785 _TDK(gl)TSTTGSILNLNLDR_
ZMYND8 Phosphorylation S781 -0.958 _TPPSTTVGS(ph)HSPPETPVLTR_

Background Information for ZMYND8:





Protein-protein Interactions for ZMYND8

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK2AP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JARID1C;KDM5C Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM8A Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS2 Cat. description Hein, Mann, Cell 2015
Category members IP bait VWA9 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZMYND8 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF687 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATAD2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCTD17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LLGL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF408 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZMYND8

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members PWWP_dom IPR000313 0.63
Category members Znf_MYND IPR002893 0.06


Protein complexes (CORUM database) featuring ZMYND8

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ZMYND8

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0001106 RNA polymerase II transcription corepressor activity Database 0.06
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0070491 repressing transcription factor binding Database 0


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