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Query: CSNK1E

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CSNK1E 0 0.605 -0.170 -0.440 0.150 0.527
CSNK1E 0 0.605 -0.170 -0.440 1.237 -0.682 -0.148

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CSNK1E Phosphorylation S389 0.394 0.817 _GAPANVS(ph)SSDLTGR_
CSNK1E Phosphorylation S363 -0.662 -0.352 _IQPAGNTS(ph)PR_
CSNK1E Ubiquitylation K141 -0.969 -0.720 _DVKPDNFLMGLGKK(gl)_
CSNK1E Ubiquitylation K43 -1.168 _LECVK(gl)TK_
CSNK1E Ubiquitylation K45 -1.168 _LECVK(gl)TK_
CSNK1E Ubiquitylation K140 -0.969 _DVKPDNFLMGLGK(gl)K_

Background Information for CSNK1E:


Pubmed-CSNK1E »
Uniprot-CSNK1E »
Biogrid-CSNK1E »
ProteomicsDB-CSNK1E »

Tumorportal-CSNK1E »
COSMIC-CSNK1E »
GenomeRNAi-CSNK1E »
Genecards-CSNK1E


Protein-protein Interactions for CSNK1E
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AXIN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAIAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAMKK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait CRY1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK1D Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK1E Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM83H Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JAK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2A Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANKRD49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARHGAP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C18orf1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C7orf45 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C7orf60 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EFHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FKBPL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OCLN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRA2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CSNK1E
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CSNK1E
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CSNK1E
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members Pathway Pathway_157 REACTOME_CIRCADIAN_CLOCK 0 0.92
Category members Pathway Pathway_1275 KEGG_CIRCADIAN_RHYTHM_MAMMAL 0 0.74
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_984 PID_HEDGEHOG_GLI_PATHWAY 0 0.1
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0034613 cellular protein localization Database 0.04
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_1151 KEGG_HEDGEHOG_SIGNALING_PATHWAY 0 0.04
Category members Pathway Pathway_1175 PID_BETA_CATENIN_DEG_PATHWAY 0 0.01
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1249 PID_CIRCADIAN_PATHWAY 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0030178 negative regulation of Wnt signaling pathway Database 0


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