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Query: RBL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RBL2 0 1.071 0.890 -0.800

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RBL2 Phosphorylation S639 0.520 _ADEICIAGS(ph)PLTPR_
RBL2 Phosphorylation S1078 0.241 0.286 _IFYYFS(ph)NSPSK_
RBL2 Phosphorylation S662 0.551 0.137 _SITS(ph)PTTLYDR_
RBL2 Phosphorylation S1080 -0.327 -0.297 _IFYYFSNS(ph)PSK_
RBL2 Phosphorylation S1112 -0.598 -0.843 _RGILLEDGSES(ph)PAKR_
RBL2 Phosphorylation S981 -1.828 _SSSTLPVPQPS(ph)SAPPT(ph)PTR_
RBL2 Phosphorylation T986 -1.219 -1.828 _SSSTLPVPQPSS(ph)APPT(ph)PTR_
RBL2 Phosphorylation S982 -2.152 _SSSTLPVPQPSS(ph)APPT(ph)PTR_

Background Information for RBL2:


Pubmed-RBL2 »
Uniprot-RBL2 »
Biogrid-RBL2 »
ProteomicsDB-RBL2 »

Tumorportal-RBL2 »
COSMIC-RBL2 »
GenomeRNAi-RBL2 »
Genecards-RBL2


Protein-protein Interactions for RBL2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCND2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCND3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RARG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNDC11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RBL2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RB_B IPR002719 0.21
Category members RB_A IPR002720 0.21
Category members RB_N IPR024599 0.21
Category members Cyclin-like IPR013763 0


Protein complexes (CORUM database) featuring RBL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5614 Emerin complex 32 Database 1.48
Category members Corum 5611 Emerin complex 24 Database 1.05
Category members Corum 5615 Emerin complex 52 Database 0.99
Category members Corum 1470 pRb2/p130-multimolecular complex (DNMT1, E2F5, SuV39H1, HDAC1, RBL2) Database 0.23
Category members Corum 5117 pRb2/p130-multimolecular complex (DNMT1, E2F4, SuV39H1, HDAC1, RBL2) Database 0.23
Category members Corum 1471 pRb2/p130-multimolecular complex (RB2, E2F5, HDAC1, SUV39H1, P300) Database 0
Category members Corum 1473 E2F5-RB2-DP1 complex Database 0
Category members Corum 5118 pRb2/p130-multimolecular complex (RB2, E2F4, HDAC1, SUV39H1, P300) Database 0
Category members Corum 5160 E2F4-p130 complex Database 0
Category members Corum 5596 LINC complex, quiescent cells Database 0


Categories featuring RBL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_313 REACTOME_MITOTIC_G1_G1_S_PHASES 0 1.45
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members Pathway Pathway_325 PID_E2F_PATHWAY 0 0.62
Category members GO Category GO:0043550 regulation of lipid kinase activity Database 0.21
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members Pathway Pathway_893 KEGG_TGF_BETA_SIGNALING_PATHWAY 0 0.14
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members Pathway Pathway_791 REACTOME_G1_PHASE 0 0.02
Category members Pathway Pathway_1097 BIOCARTA_ETS_PATHWAY 0 0
Category members Pathway Pathway_619 SA_PTEN_PATHWAY 0 0
Category members Pathway Pathway_869 REACTOME_G0_AND_EARLY_G1 0 0


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