bioLOGIC Category
Results for the Category
pRb2/p130-multimolecular complex (DNMT1, E2F4, SuV39H1, HDAC1, RBL2)
(5117)
| RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
| W |
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| Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
|
DNMT1
|
2
|
0.150
|
-0.150
|
|
0.077
|
-0.109
|
-1.422
|
0.572
|
|
DNMT1
|
2
|
0.150
|
-0.150
|
0.134
|
|
|
-0.347
|
-0.054
|
|
HDAC1
|
1
|
-1.980
|
4.450
|
|
|
|
|
|
|
HDAC1
|
1
|
-1.980
|
4.450
|
-0.122
|
0.307
|
0.969
|
0.094
|
0.191
|
|
RBL2
|
0
|
0.890
|
-0.800
|
|
|
|
|
|
|
E2F4
|
0
|
0.930
|
-0.810
|
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| Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
|
DNMT1
|
Phosphorylation
|
S127
|
-0.755
|
-0.836
|
_VGM(ox)ADANS(ph)PPKPLSKPR_
|
|
DNMT1
|
Phosphorylation
|
S143
|
0.877
|
0.220
|
_SKS(ph)DGEAKPEPSPSPR_
|
|
DNMT1
|
Phosphorylation
|
S152
|
-0.685
|
-1.347
|
_SDGEAKPEPS(ph)PSPR_
|
|
DNMT1
|
Phosphorylation
|
S154
|
-1.926
|
-0.876
|
_SDGEAKPEPSPS(ph)PR_
|
|
DNMT1
|
Ubiquitylation
|
K586
|
1.686
|
3.368
|
_DLIK(gl)LAGVTLGQR_
|
|
DNMT1
|
Ubiquitylation
|
K675
|
1.267
|
0.915
|
_DMVK(gl)FGGSGR_
|
|
DNMT1
|
Phosphorylation
|
S714
|
-0.773
|
-0.554
|
_EADDDEEVDDNIPEMPS(ph)PKK_
|
|
DNMT1
|
Phosphorylation
|
S954
|
-0.318
|
0.057
|
_LSS(ph)PVKRPR_
|
|
DNMT1
|
Ubiquitylation
|
K961
|
-3.166
|
|
_K(gl)EPVDEDLYPEHYR_
|
|
DNMT1
|
Ubiquitylation
|
K981
|
-0.298
|
-1.482
|
_YSDYIK(gl)GSNLDAPEPYR_
|
|
DNMT1
|
Ubiquitylation
|
K997
|
0.042
|
0.154
|
_IK(gl)EIFCPK_
|
|
DNMT1
|
Ubiquitylation
|
K1483
|
1.983
|
-0.103
|
_GVCSCVEAGK(gl)ACDPAAR_
|
|
E2F4
|
Phosphorylation
|
T14
|
|
-2.100
|
_(ac)AEAGPQAPPPPGT(ph)PSR_
|
|
E2F4
|
Phosphorylation
|
S16
|
-2.158
|
-1.655
|
_(ac)AEAGPQAPPPPGTPS(ph)R_
|
|
HDAC1
|
Ubiquitylation
|
K50
|
0.036
|
|
_K(gl)MEIYRPHK_
|
|
HDAC1
|
Ubiquitylation
|
K66
|
|
-0.593
|
_ANAEEMTK(gl)YHSDDYIK_
|
|
HDAC1
|
Ubiquitylation
|
K74
|
0.620
|
-1.473
|
_YHSDDYIK(gl)FLR_
|
|
HDAC1
|
Ubiquitylation
|
K89
|
0.749
|
-0.241
|
_SIRPDNMSEYSK(gl)QMQR_
|
|
HDAC1
|
Phosphorylation
|
S393
|
-1.133
|
-1.144
|
_M(ox)LPHAPGVQM(ox)QAIPEDAIPEES(ph)GDEDEDDPDKR_
|
|
HDAC1
|
Phosphorylation
|
S409
|
1.326
|
1.144
|
_ISICS(ph)SDKR_
|
|
HDAC1
|
Phosphorylation
|
S410
|
1.326
|
1.144
|
_ISICS(ph)SDKR_
|
|
HDAC1
|
Ubiquitylation
|
K412
|
0.642
|
-0.744
|
_ISICSSDK(gl)R_
|
|
RBL2
|
Phosphorylation
|
S639
|
|
0.520
|
_ADEICIAGS(ph)PLTPR_
|
|
RBL2
|
Phosphorylation
|
S662
|
0.551
|
0.137
|
_SITS(ph)PTTLYDR_
|
|
RBL2
|
Phosphorylation
|
S981
|
|
-1.828
|
_SSSTLPVPQPS(ph)SAPPT(ph)PTR_
|
|
RBL2
|
Phosphorylation
|
S982
|
|
-2.152
|
_SSSTLPVPQPSS(ph)APPT(ph)PTR_
|
|
RBL2
|
Phosphorylation
|
T986
|
-1.219
|
-1.828
|
_SSSTLPVPQPSS(ph)APPT(ph)PTR_
|
|
RBL2
|
Phosphorylation
|
S1078
|
0.241
|
0.286
|
_IFYYFS(ph)NSPSK_
|
|
RBL2
|
Phosphorylation
|
S1080
|
-0.327
|
-0.297
|
_IFYYFSNS(ph)PSK_
|
|
RBL2
|
Phosphorylation
|
S1112
|
-0.598
|
-0.843
|
_RGILLEDGSES(ph)PAKR_
|
© Copyright Svejstrup Laboratory 2015