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Query: KAT2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KAT2B 1 4.178 -0.980 2.090

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KAT2B Phosphorylation S117 2.088 _NPNPS(ph)PTPPR_

Background Information for KAT2B:


Pubmed-KAT2B »
Uniprot-KAT2B »
Biogrid-KAT2B »
ProteomicsDB-KAT2B »

Tumorportal-KAT2B »
COSMIC-KAT2B »
GenomeRNAi-KAT2B »
Genecards-KAT2B


Protein-protein Interactions for KAT2B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATXN7L3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC101 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TADA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TADA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF6L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KAT2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members GNAT_dom IPR000182 0
Category members Acyl_CoA_acyltransferase IPR016181 0


Protein complexes (CORUM database) featuring KAT2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3137 MASH1 promoter-coactivator complex Database 5.32
Category members Corum 3066 RNA polymerase II complex, chromatin structure modifying Database 0.92
Category members Corum 5373 Chromatin remodeling complex (TACC2, TACC3, PCAF) Database 0.52
Category members Corum 3062 RNA polymerase II complex, incomplete (CBP, RPBI, PCAF, BAF47), chromatin structure modifying Database 0.33
Category members Corum 4 Multisubunit ACTR coactivator complex Database 0.31
Category members Corum 1338 FOXO3-PCAF complex, oxidative stress stimulated Database 0.29
Category members Corum 3061 RNA polymerase II complex (CBP, PCAF, RPB1, BAF47, CYCC, CDK8), chromatin structure modifying Database 0.18
Category members Corum 471 PCAF complex Database 0.08
Category members Corum 477 PCAF complex Database 0.08
Category members Corum 3142 CAMK2-delta-MASH1 promoter-coactivator complex Database 0.07
Category members Corum 2641 p300/CBP-PCAF-MyoD complex Database 0


Categories featuring KAT2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0006338 chromatin remodeling Database 4.95
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members Pathway Pathway_346 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION 0 3.42
Category members GO Category GO:0006360 transcription from RNA polymerase I promoter Database 2.66
Category members GO Category GO:0006361 transcription initiation from RNA polymerase I promoter Database 2.41
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0016573 histone acetylation Database 1.24
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members GO Category GO:0042641 actomyosin Database 0.9
Category members Pathway Pathway_308 PID_AR_TF_PATHWAY 0 0.86
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members Pathway Pathway_325 PID_E2F_PATHWAY 0 0.62
Category members GO Category GO:0004402 histone acetyltransferase activity Database 0.56
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members Pathway Pathway_744 PID_HDAC_CLASSIII_PATHWAY 0 0.34
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members GO Category GO:0006473 protein acetylation Database 0.3
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_891 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION 0 0.24
Category members Pathway Pathway_789 REACTOME_SIGNALING_BY_NOTCH1 0 0.22
Category members Pathway Pathway_945 BIOCARTA_VDR_PATHWAY 0 0.22
Category members GO Category GO:0003712 transcription cofactor activity Database 0.21
Category members GO Category GO:0042826 histone deacetylase binding Database 0.16
Category members GO Category GO:0000123 histone acetyltransferase complex Database 0.15
Category members Pathway Pathway_824 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 0 0.14
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0018076 N-terminal peptidyl-lysine acetylation Database 0.1
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members Pathway Pathway_381 BIOCARTA_RARRXR_PATHWAY 0 0.08
Category members Pathway Pathway_113 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 0 0.08
Category members GO Category GO:0008080 N-acetyltransferase activity Database 0.06
Category members GO Category GO:0016407 acetyltransferase activity Database 0.05
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0018393 internal peptidyl-lysine acetylation Database 0.01
Category members Pathway Pathway_890 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY 0 0
Category members Pathway Pathway_892 KEGG_NOTCH_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_939 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION 0 0
Category members Pathway Pathway_946 PID_RETINOIC_ACID_PATHWAY 0 0
Category members GO Category GO:0000125 PCAF complex Database 0
Category members GO Category GO:0004468 lysine N-acetyltransferase activity Database 0
Category members GO Category GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity Database 0
Category members GO Category GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0018394 peptidyl-lysine acetylation Database 0
Category members GO Category GO:0031672 A band Database 0
Category members GO Category GO:0031674 I band Database 0
Category members GO Category GO:0043966 histone H3 acetylation Database 0
Category members GO Category GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity Database 0


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