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REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION
(Pathway_891)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
SNW1 1 -2.350 4.480
SNW1 1 -2.350 4.480 -0.520 -1.264 -0.234 -2.391 -0.788
CCND1 1 -1.820 3.470
KAT2B 1 -0.980 2.090
MOV10 1 -1.600 2.780 0.306 -0.640 0.908 0.935
CREBBP 0 0.840 -0.950 -3.889 -1.071
TNRC6C 0 -0.980 1.140
TNRC6B 0 -1.680 2.330
EP300 0 -1.210 1.320 -1.089 -1.694 -0.723
E2F3 0 0.000 0.020
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
MAML1 0 0.470 -0.390
RBPJ 0 1.900 -0.160 -0.367 0.284 0.723 -0.090 0.134
TFDP1 0 -0.430 0.060 -1.111 0.446 -1.279 -0.496

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CCND1 Ubiquitylation K33 -0.490 _AMLK(gl)AEETCAPSVSYFK_
CCND1 Ubiquitylation K46 -1.016 -0.036 _AEETCAPSVSYFK(gl)CVQK_
CCND1 Ubiquitylation K95 -0.733 -0.137 _FLSLEPVK(gl)K_
CCND1 Ubiquitylation K96 -0.846 -0.155 _FLSLEPVKK(gl)_
CCND1 Ubiquitylation K238 0.245 _VIK(gl)CDPDCLR_
CREBBP Phosphorylation S2093 0.037 0.097 _SIS(ph)PSALQDLLR_
E2F3 Ubiquitylation K188 -0.267 _TRYDTSLGLLTK(gl)K_
E2F3 Ubiquitylation K189 -0.267 _TRYDTSLGLLTK(gl)K_
EP300 Phosphorylation S1038 -0.672 -0.349 _TEIKEEEDQPSTSATQSS(ph)PAPGQSK_
EP300 Phosphorylation S1726 0.994 0.627 _LGLGLDDESNNQQAAATQS(ph)PGDSRR_
EP300 Phosphorylation S2328 -1.092 0.725 _PQSQPPHSSPS(ph)PR_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
KAT2B Phosphorylation S117 2.088 _NPNPS(ph)PTPPR_
MAML1 Phosphorylation S45 1.371 0.474 _YEAVS(ph)PERLELER_
MOV10 Ubiquitylation K90 -0.738 -1.666 _WADVRFPEK(gl)R_
MOV10 Ubiquitylation K94 0.142 _MK(gl)LGSDISK_
MOV10 Ubiquitylation K489 -1.796 _DVPLLPSDVK(gl)LK_
MOV10 Ubiquitylation K491 -1.931 -1.796 _DVPLLPSDVKLK(gl)_
MOV10 Ubiquitylation K816 0.014 _LLLAPSSK(gl)K_
MOV10 Ubiquitylation K817 0.014 -0.549 _LLLAPSSKK(gl)_
MOV10 Ubiquitylation K846 -0.101 0.119 _YCITK(gl)LDR_
MOV10 Ubiquitylation K858 0.014 -0.307 _GLDDIK(gl)DLK_
MOV10 Phosphorylation S969 -0.003 -0.113 _LS(ph)PSTSGPHSHDYLPQER_
SNW1 Ubiquitylation K193 1.500 _YTPSQQGVAFNSGAK(gl)QR_
SNW1 Phosphorylation S224 -0.528 0.034 _GPPS(ph)PPAPVMHSPS(ph)RK_
SNW1 Phosphorylation S232 -1.645 -1.722 _GPPS(ph)PPAPVMHS(ph)PSR_
SNW1 Phosphorylation S234 -1.881 _GPPS(ph)PPAPVMHSPS(ph)RK_
TFDP1 Phosphorylation S23 -0.667 -0.353 _VFIDQNLS(ph)PGK_
TFDP1 Ubiquitylation K320 -0.549 0.052 _MGMACGLESGSCSAEDLK(gl)MAR_
TNRC6B Phosphorylation S1432 -1.203 -0.920 _GGS(ph)PYNQFDIIPGDTLGGHTGPAGDSWLPAK_
TNRC6B Phosphorylation S1461 -0.788 -0.865 _GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKS(ph)PPTNK_
TNRC6B Phosphorylation T1464 -0.696 _GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPT(ph)NK_
TNRC6B Phosphorylation S1512 0.304 _GIQNIDPESDPYVTPGSVLGGTATS(ph)PIVDTDHQLLR_
TNRC6C Phosphorylation S714 -0.816 -0.786 _DSSEATGWEEPS(ph)PPSIR_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_


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