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Query: TFDP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TFDP1 0 -3.898 -0.430 0.060 -1.111 0.446 -1.279 -0.496

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TFDP1 Ubiquitylation K320 -0.549 0.052 _MGMACGLESGSCSAEDLK(gl)MAR_
TFDP1 Phosphorylation S23 -0.667 -0.353 _VFIDQNLS(ph)PGK_

Background Information for TFDP1:


Pubmed-TFDP1 »
Uniprot-TFDP1 »
Biogrid-TFDP1 »
ProteomicsDB-TFDP1 »

Tumorportal-TFDP1 »
COSMIC-TFDP1 »
GenomeRNAi-TFDP1 »
Genecards-TFDP1


Protein-protein Interactions for TFDP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait L3MBTL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait COMMD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E2F6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GGA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GMNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L3MBTL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIER2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RYBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TFDP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members E2F_TDP IPR003316 0.45
Category members Transc_factor_DP_C IPR014889 0.18
Category members Transcrpt_fac_DP IPR015648 0.18


Protein complexes (CORUM database) featuring TFDP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1473 E2F5-RB2-DP1 complex Database 0
Category members Corum 1474 SMAD3/4-E2F4/5-p107-DP1 complex Database 0
Category members Corum 2975 SMAD3-E2F4/5-p107-DP1 complex Database 0
Category members Corum 3900 GABP(gamma)1-E2F1-DP1 complex Database 0


Categories featuring TFDP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members Pathway Pathway_322 REACTOME_G1_S_TRANSITION 0 1.77
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_313 REACTOME_MITOTIC_G1_G1_S_PHASES 0 1.45
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_777 REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 0 0.89
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_325 PID_E2F_PATHWAY 0 0.62
Category members Pathway Pathway_326 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION 0 0.49
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members Pathway Pathway_332 REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION 0 0.36
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members Pathway Pathway_891 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION 0 0.24
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members Pathway Pathway_406 PID_RB_1PATHWAY 0 0.21
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members Pathway Pathway_802 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER 0 0.17
Category members Pathway Pathway_893 KEGG_TGF_BETA_SIGNALING_PATHWAY 0 0.14
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_312 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 0 0.11
Category members Pathway Pathway_973 BIOCARTA_P27_PATHWAY 0 0.1
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members Pathway Pathway_113 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 0 0.08
Category members Pathway Pathway_808 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION 0 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members Pathway Pathway_791 REACTOME_G1_PHASE 0 0.02
Category members Pathway Pathway_1250 BIOCARTA_SKP2E2F_PATHWAY 0 0
Category members Pathway Pathway_589 BIOCARTA_RACCYCD_PATHWAY 0 0
Category members Pathway Pathway_745 BIOCARTA_G1_PATHWAY 0 0
Category members Pathway Pathway_869 REACTOME_G0_AND_EARLY_G1 0 0
Category members Pathway Pathway_970 BIOCARTA_CELLCYCLE_PATHWAY 0 0
Category members Pathway Pathway_988 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS 0 0
Category members Pathway Pathway_990 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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