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Query: MOV10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MOV10 1 4.434 -1.600 2.780 0.306 -0.640 0.908 0.935

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MOV10 Ubiquitylation K846 -0.101 0.119 _YCITK(gl)LDR_
MOV10 Phosphorylation S969 -0.003 -0.113 _LS(ph)PSTSGPHSHDYLPQER_
MOV10 Ubiquitylation K858 0.014 -0.307 _GLDDIK(gl)DLK_
MOV10 Ubiquitylation K817 0.014 -0.549 _LLLAPSSKK(gl)_
MOV10 Ubiquitylation K90 -0.738 -1.666 _WADVRFPEK(gl)R_
MOV10 Ubiquitylation K489 -1.796 _DVPLLPSDVK(gl)LK_
MOV10 Ubiquitylation K491 -1.931 -1.796 _DVPLLPSDVKLK(gl)_
MOV10 Ubiquitylation K94 0.142 _MK(gl)LGSDISK_
MOV10 Ubiquitylation K816 0.014 _LLLAPSSK(gl)K_

Background Information for MOV10:


Pubmed-MOV10 »
Uniprot-MOV10 »
Biogrid-MOV10 »
ProteomicsDB-MOV10 »

Tumorportal-MOV10 »
COSMIC-MOV10 »
GenomeRNAi-MOV10 »
Genecards-MOV10


Protein-protein Interactions for MOV10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E4F1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXW11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTSCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HNRNPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRR11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRA2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3HAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFC3H1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MOV10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83


Protein complexes (CORUM database) featuring MOV10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 5380 TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) Database 5.3
Category members Corum 5378 TRBP containing complex (DICER, TRBP, AGO2, RPL7A, EIF6, MOV10) Database 0


Categories featuring MOV10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members GO Category GO:0008543 fibroblast growth factor receptor signaling pathway Database 0.29
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members Pathway Pathway_891 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION 0 0.24
Category members Pathway Pathway_113 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 0 0.08
Category members GO Category GO:0000932 cytoplasmic mRNA processing body Database 0.08
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0035279 mRNA cleavage involved in gene silencing by miRNA Database 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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