Results for the Category
mRNA cleavage involved in gene silencing by miRNA
(GO:0035279)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| AGO2 | 1 | 0.370 | -0.620 | 0.303 | -0.277 | -0.950 | 0.328 | |
| MOV10 | 1 | -1.600 | 2.780 | 0.306 | -0.640 | 0.908 | 0.935 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| AGO2 | Ubiquitylation | K381 | 0.665 | _SAPDRQEEISK(gl)LMR_ | |
| AGO2 | Phosphorylation | S387 | -0.656 | _SAS(ph)FNTDPYVR_ | |
| AGO2 | Ubiquitylation | K550 | 0.445 | 1.991 | _VGDTVLGMATQCVQMK(gl)NVQR_ |
| AGO2 | Ubiquitylation | K720 | -1.047 | 0.670 | _LFCTDK(gl)NER_ |
| AGO2 | Ubiquitylation | K726 | 0.458 | 0.936 | _VGK(gl)SGNIPAGTTVDTK_ |
| MOV10 | Ubiquitylation | K90 | -0.738 | -1.666 | _WADVRFPEK(gl)R_ |
| MOV10 | Ubiquitylation | K94 | 0.142 | _MK(gl)LGSDISK_ | |
| MOV10 | Ubiquitylation | K489 | -1.796 | _DVPLLPSDVK(gl)LK_ | |
| MOV10 | Ubiquitylation | K491 | -1.931 | -1.796 | _DVPLLPSDVKLK(gl)_ |
| MOV10 | Ubiquitylation | K816 | 0.014 | _LLLAPSSK(gl)K_ | |
| MOV10 | Ubiquitylation | K817 | 0.014 | -0.549 | _LLLAPSSKK(gl)_ |
| MOV10 | Ubiquitylation | K846 | -0.101 | 0.119 | _YCITK(gl)LDR_ |
| MOV10 | Ubiquitylation | K858 | 0.014 | -0.307 | _GLDDIK(gl)DLK_ |
| MOV10 | Phosphorylation | S969 | -0.003 | -0.113 | _LS(ph)PSTSGPHSHDYLPQER_ |
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