bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: MAML1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAML1 0 1.845 0.470 -0.390

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAML1 Phosphorylation S45 1.371 0.474 _YEAVS(ph)PERLELER_

Background Information for MAML1:


Pubmed-MAML1 »
Uniprot-MAML1 »
Biogrid-MAML1 »
ProteomicsDB-MAML1 »

Tumorportal-MAML1 »
COSMIC-MAML1 »
GenomeRNAi-MAML1 »
Genecards-MAML1


Protein-protein Interactions for MAML1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HUWE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NIPBL Cat. description Hein, Mann, Cell 2015
Category members IP bait RBPJ Cat. description Hein, Mann, Cell 2015
Category members IP bait RBPJ Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAML1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Neuroggenic_mastermind-like_N IPR019082 0.04


Protein complexes (CORUM database) featuring MAML1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2639 HES1 promoter-Notch enhancer complex Database 0.45
Category members Corum 2890 Notch1-fraction 30 complex Database 0.01
Category members Corum 2897 RBPJ-NotchIC-Mastermind complex Database 0.01
Category members Corum 3113 MAML1-RBP-Jkappa-Notch1 complex Database 0.01


Categories featuring MAML1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members Pathway Pathway_849 PID_NOTCH_PATHWAY 0 0.29
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_891 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION 0 0.24
Category members Pathway Pathway_789 REACTOME_SIGNALING_BY_NOTCH1 0 0.22
Category members Pathway Pathway_824 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 0 0.14
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0060928 atrioventricular node cell development Database 0.11
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members Pathway Pathway_113 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 0 0.08
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0051149 positive regulation of muscle cell differentiation Database 0.04
Category members GO Category GO:0010831 positive regulation of myotube differentiation Database 0.03
Category members GO Category GO:0002193 MAML1-RBP-Jkappa- ICN1 complex Database 0.01
Category members Pathway Pathway_119 PID_HES_HEY_PATHWAY 0 0
Category members Pathway Pathway_890 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY 0 0
Category members Pathway Pathway_892 KEGG_NOTCH_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0003162 atrioventricular node development Database 0
Category members GO Category GO:0042605 peptide antigen binding Database 0
Category members GO Category GO:0045445 myoblast differentiation Database 0


.

© Copyright Svejstrup Laboratory 2015