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Query: TNRC6C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TNRC6C 0 -0.462 -0.980 1.140

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TNRC6C Phosphorylation S714 -0.816 -0.786 _DSSEATGWEEPS(ph)PPSIR_

Background Information for TNRC6C:


Pubmed-TNRC6C »
Uniprot-TNRC6C »
Biogrid-TNRC6C »
ProteomicsDB-TNRC6C »

Tumorportal-TNRC6C »
COSMIC-TNRC6C »
GenomeRNAi-TNRC6C »
Genecards-TNRC6C


Protein-protein Interactions for TNRC6C
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AURKA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNB2L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NR2E1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TNRC6C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBA/Ts_N IPR000449 0.34
Category members UBA-like IPR009060 0.17
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04
Category members Argonaute_hook_dom IPR019486 0


Protein complexes (CORUM database) featuring TNRC6C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TNRC6C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members GO Category GO:0008543 fibroblast growth factor receptor signaling pathway Database 0.29
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members Pathway Pathway_891 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION 0 0.24
Category members GO Category GO:0035162 embryonic hemopoiesis Database 0.17
Category members Pathway Pathway_379 REACTOME_REGULATORY_RNA_PATHWAYS 0 0.12
Category members GO Category GO:0001706 endoderm formation Database 0.08
Category members Pathway Pathway_113 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 0 0.08
Category members GO Category GO:0007492 endoderm development Database 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0035278 negative regulation of translation involved in gene silencing by miRNA Database 0
Category members GO Category GO:0048568 embryonic organ development Database 0
Category members GO Category GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening Database 0
Category members GO Category GO:0060964 regulation of gene silencing by miRNA Database 0


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