Results for the Category
negative regulation of translation involved in gene silencing by miRNA
(GO:0035278)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| AGO4 | 2 | 2.110 | -1.140 | |||||
| AGO4 | 2 | 2.110 | -1.140 | 0.303 | -0.277 | -0.950 | 0.328 | |
| AGO1 | 1 | 1.720 | -1.200 | |||||
| AGO1 | 1 | 1.720 | -1.200 | 0.303 | -0.277 | -0.950 | 0.328 | |
| AGO2 | 1 | 0.370 | -0.620 | 0.303 | -0.277 | -0.950 | 0.328 | |
| ZFP36 | 1 | -1.860 | 3.010 | |||||
| TNRC6C | 0 | -0.980 | 1.140 | |||||
| AGO3 | 0 | 0.130 | -0.440 | |||||
| RBM4 | 0 | -0.070 | 0.200 | 0.658 | 0.120 | |||
| RBM4 | 0 | -0.070 | 0.200 | -0.149 | 0.399 | 0.199 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| AGO1 | Ubiquitylation | K364 | 0.517 | 1.241 | _LTDNQTSTMIK(gl)ATAR_ |
| AGO1 | Ubiquitylation | K381 | 0.665 | _SAPDRQEEISK(gl)LMR_ | |
| AGO1 | Phosphorylation | S387 | -0.656 | _SAS(ph)FNTDPYVR_ | |
| AGO1 | Ubiquitylation | K550 | 0.445 | 1.991 | _VGDTVLGMATQCVQMK(gl)NVQR_ |
| AGO1 | Ubiquitylation | K720 | -1.047 | 0.670 | _LFCTDK(gl)NER_ |
| AGO1 | Ubiquitylation | K726 | 0.458 | 0.936 | _VGK(gl)SGNIPAGTTVDTK_ |
| AGO2 | Ubiquitylation | K381 | 0.665 | _SAPDRQEEISK(gl)LMR_ | |
| AGO2 | Phosphorylation | S387 | -0.656 | _SAS(ph)FNTDPYVR_ | |
| AGO2 | Ubiquitylation | K550 | 0.445 | 1.991 | _VGDTVLGMATQCVQMK(gl)NVQR_ |
| AGO2 | Ubiquitylation | K720 | -1.047 | 0.670 | _LFCTDK(gl)NER_ |
| AGO2 | Ubiquitylation | K726 | 0.458 | 0.936 | _VGK(gl)SGNIPAGTTVDTK_ |
| AGO3 | Ubiquitylation | K364 | 0.517 | 1.241 | _LTDNQTSTMIK(gl)ATAR_ |
| AGO4 | Ubiquitylation | K364 | 0.517 | 1.241 | _LTDNQTSTMIK(gl)ATAR_ |
| AGO4 | Ubiquitylation | K381 | 0.665 | _SAPDRQEEISK(gl)LMR_ | |
| AGO4 | Phosphorylation | S387 | -0.656 | _SAS(ph)FNTDPYVR_ | |
| AGO4 | Ubiquitylation | K550 | 0.445 | 1.991 | _VGDTVLGMATQCVQMK(gl)NVQR_ |
| AGO4 | Ubiquitylation | K720 | -1.047 | 0.670 | _LFCTDK(gl)NER_ |
| AGO4 | Ubiquitylation | K726 | 0.458 | 0.936 | _VGK(gl)SGNIPAGTTVDTK_ |
| RBM4 | Phosphorylation | S86 | 0.208 | 0.329 | _LHVGNIS(ph)PTCTNK_ |
| RBM4 | Phosphorylation | T88 | 0.272 | 0.180 | _LHVGNISPT(ph)CTNK_ |
| RBM4 | Ubiquitylation | K92 | -1.041 | _LHVGNISPTCTNK(gl)ELR_ | |
| RBM4 | Ubiquitylation | K139 | 0.371 | 0.223 | _GLDNTEFQGK(gl)R_ |
| TNRC6C | Phosphorylation | S714 | -0.816 | -0.786 | _DSSEATGWEEPS(ph)PPSIR_ |
| ZFP36 | Phosphorylation | S93 | -0.357 | _LGPELSPSPTS(ph)PTATSTTPSR_ | |
| ZFP36 | Phosphorylation | T95 | -0.633 | -0.624 | _LGPELSPSPTSPT(ph)ATSTTPSR_ |
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