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Query: RBM4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RBM4 0 1.845 -0.070 0.200 0.658 0.120
RBM4 0 1.845 -0.070 0.200 -0.149 0.399 0.199

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RBM4 Phosphorylation S86 0.208 0.329 _LHVGNIS(ph)PTCTNK_
RBM4 Ubiquitylation K139 0.371 0.223 _GLDNTEFQGK(gl)R_
RBM4 Phosphorylation T88 0.272 0.180 _LHVGNISPT(ph)CTNK_
RBM4 Ubiquitylation K92 -1.041 _LHVGNISPTCTNK(gl)ELR_

Background Information for RBM4:





Protein-protein Interactions for RBM4

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARX Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf43;RTFDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC88A Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK18 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DNAJC11 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21A Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF7 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MKNK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH13 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAX6 Cat. description Hein, Mann, Cell 2015
Category members IP bait PIP4K2C Cat. description Hein, Mann, Cell 2015
Category members IP bait POLK Cat. description Hein, Mann, Cell 2015
Category members IP bait PPIA Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM4 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMAD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS26A Cat. description Hein, Mann, Cell 2015
Category members IP bait DDX31 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0020 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPP25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF317 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RBM4

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members Znf_CCHC IPR001878 1.51


Protein complexes (CORUM database) featuring RBM4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RBM4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0000381 regulation of alternative mRNA splicing, via spliceosome Database 0.5
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0003730 mRNA 3'-UTR binding Database 0.24
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0051149 positive regulation of muscle cell differentiation Database 0.04
Category members GO Category GO:0032055 negative regulation of translation in response to stress Database 0
Category members GO Category GO:0035198 miRNA binding Database 0
Category members GO Category GO:0035278 negative regulation of translation involved in gene silencing by miRNA Database 0
Category members GO Category GO:0043153 entrainment of circadian clock by photoperiod Database 0
Category members GO Category GO:0045947 negative regulation of translational initiation Database 0
Category members GO Category GO:0046685 response to arsenic-containing substance Database 0
Category members GO Category GO:0046822 regulation of nucleocytoplasmic transport Database 0
Category members GO Category GO:0051403 stress-activated MAPK cascade Database 0


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