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Query: ZFP36

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZFP36 1 2.020 -1.860 3.010

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZFP36 Phosphorylation S93 -0.357 _LGPELSPSPTS(ph)PTATSTTPSR_
ZFP36 Phosphorylation T95 -0.633 -0.624 _LGPELSPSPTSPT(ph)ATSTTPSR_

Background Information for ZFP36:


Pubmed-ZFP36 »
Uniprot-ZFP36 »
Biogrid-ZFP36 »
ProteomicsDB-ZFP36 »

Tumorportal-ZFP36 »
COSMIC-ZFP36 »
GenomeRNAi-ZFP36 »
Genecards-ZFP36


Protein-protein Interactions for ZFP36
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in ZFP36
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_CCCH IPR000571 0.03


Protein complexes (CORUM database) featuring ZFP36
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1386 TTP-AGO4 complex Database 0
Category members Corum 1387 TTP-AGO2 complex Database 0


Categories featuring ZFP36
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_781 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 0 2.04
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members Pathway Pathway_846 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP 0 0.18
Category members GO Category GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Database 0.17
Category members GO Category GO:0045638 negative regulation of myeloid cell differentiation Database 0.1
Category members GO Category GO:0043488 regulation of mRNA stability Database 0.07
Category members GO Category GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening Database 0.06
Category members GO Category GO:0006402 mRNA catabolic process Database 0.02
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0003727 single-stranded RNA binding Database 0
Category members GO Category GO:0017091 AU-rich element binding Database 0
Category members GO Category GO:0019957 C-C chemokine binding Database 0
Category members GO Category GO:0032680 regulation of tumor necrosis factor production Database 0
Category members GO Category GO:0035278 negative regulation of translation involved in gene silencing by miRNA Database 0
Category members GO Category GO:0035925 mRNA 3'-UTR AU-rich region binding Database 0
Category members GO Category GO:0042594 response to starvation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050728 negative regulation of inflammatory response Database 0
Category members GO Category GO:0050779 RNA destabilization Database 0
Category members GO Category GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening Database 0
Category members GO Category GO:0070935 3'-UTR-mediated mRNA stabilization Database 0


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