Results for the Category
cyclin-dependent protein serine/threonine kinase inhibitor activity
(GO:0004861)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| KAT2B | 1 | -0.980 | 2.090 | |||||
| CDKN1A | 0 | 1.080 | -0.750 | |||||
| CDKN2A | 0 | -0.080 | -0.260 | -0.556 | -1.080 | -3.270 | -1.110 | |
| CASP3 | 0 | 0.570 | -0.390 | |||||
| HEXIM2 | 0 | -0.490 | 1.310 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CASP3 | Ubiquitylation | K11 | -0.053 | -0.687 | _(ac)MENTENSVDSK(gl)SIK_ |
| CASP3 | Ubiquitylation | K14 | -0.455 | -0.687 | _SIK(gl)NLEPK_ |
| CASP3 | Ubiquitylation | K57 | -0.304 | -1.817 | _NFHK(gl)STGMTSR_ |
| CASP3 | Ubiquitylation | K82 | -0.268 | -0.605 | _NLK(gl)YEVR_ |
| CDKN1A | Ubiquitylation | K188 | -2.505 | -1.077 | _QTSMTDFYHSK(gl)R_ |
| HEXIM2 | Phosphorylation | S14 | 0.794 | _(ac)MMATPNQTACNAES(ph)PVALEEAK_ | |
| HEXIM2 | Phosphorylation | S76 | 0.437 | -0.036 | _TQS(ph)PGGCSAEAVLAR_ |
| KAT2B | Phosphorylation | S117 | 2.088 | _NPNPS(ph)PTPPR_ |
.
© Copyright Svejstrup Laboratory 2015