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Query: HEXIM2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HEXIM2 0 2.541 -0.490 1.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HEXIM2 Phosphorylation S14 0.794 _(ac)MMATPNQTACNAES(ph)PVALEEAK_
HEXIM2 Phosphorylation S76 0.437 -0.036 _TQS(ph)PGGCSAEAVLAR_

Background Information for HEXIM2:


Pubmed-HEXIM2 »
Uniprot-HEXIM2 »
Biogrid-HEXIM2 »
ProteomicsDB-HEXIM2 »

Tumorportal-HEXIM2 »
COSMIC-HEXIM2 »
GenomeRNAi-HEXIM2 »
Genecards-HEXIM2


Protein-protein Interactions for HEXIM2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FERD3L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HEXIM2
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring HEXIM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HEXIM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0017069 snRNA binding Database 0.96
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity Database 0
Category members GO Category GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity Database 0


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