bioLOGIC Category
Results for the Category
TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2)
(5193)
| RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
| W |
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| Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
|
IKBKG
|
0
|
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NFKB2
|
0
|
1.750
|
-0.820
|
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KPNA3
|
0
|
-0.380
|
0.240
|
0.631
|
-0.390
|
0.376
|
0.651
|
-0.147
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NFKB1
|
0
|
0.720
|
-0.810
|
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NFKBIE
|
0
|
1.270
|
-0.670
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RELA
|
0
|
-1.130
|
1.600
|
0.793
|
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CHUK
|
0
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-0.480
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| Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
|
CHUK
|
Ubiquitylation
|
K296
|
|
-1.637
|
_GGPVDLTLK(gl)QPR_
|
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IKBKG
|
Ubiquitylation
|
K285
|
-1.202
|
-0.389
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_QEVIDKLK(gl)EEAEQHK_
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IKBKG
|
Ubiquitylation
|
K309
|
0.123
|
0.725
|
_AQADIYK(gl)ADFQAER_
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IKBKG
|
Ubiquitylation
|
K344
|
|
0.060
|
_LK(gl)ASCQESAR_
|
|
IKBKG
|
Phosphorylation
|
S387
|
-1.270
|
-1.418
|
_S(ph)PPEEPPDFCCPK_
|
|
KPNA3
|
Phosphorylation
|
S56
|
|
0.255
|
_NVPQEES(ph)LEDSDVDADFK_
|
|
KPNA3
|
Phosphorylation
|
S60
|
0.014
|
0.081
|
_RNVPQEESLEDS(ph)DVDADFK_
|
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NFKB1
|
Phosphorylation
|
S907
|
-0.025
|
0.113
|
_TTSQAHSLPLS(ph)PASTR_
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NFKB2
|
Ubiquitylation
|
K741
|
|
-2.393
|
_GHTPLDLTCSTK(gl)VK_
|
|
NFKB2
|
Ubiquitylation
|
K743
|
-0.624
|
|
_GHTPLDLTCSTKVK(gl)_
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NFKBIE
|
Ubiquitylation
|
K316
|
|
-0.248
|
_ALVLK(gl)GASR_
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