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Query: RASGRP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RASGRP3 0 0.878 0.570 0.240

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RASGRP3 Phosphorylation S390 0.183 0.695 _SPTS(ph)PTTPNK_

Background Information for RASGRP3:


Pubmed-RASGRP3 »
Uniprot-RASGRP3 »
Biogrid-RASGRP3 »
ProteomicsDB-RASGRP3 »

Tumorportal-RASGRP3 »
COSMIC-RASGRP3 »
GenomeRNAi-RASGRP3 »
Genecards-RASGRP3


Protein-protein Interactions for RASGRP3
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in RASGRP3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PE/DAG-bd IPR002219 0.63
Category members DAG/PE-bd IPR020454 0.18
Category members Ras-like_Gua-exchang_fac_N IPR000651 0
Category members RASGEF_cat_dom IPR001895 0
Category members EF_hand_dom IPR002048 0
Category members Ras_GEF_dom IPR023578 0


Protein complexes (CORUM database) featuring RASGRP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RASGRP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_660 REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 0 2.12
Category members Pathway Pathway_706 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 0 1.96
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0017016 Ras GTPase binding Database 1.28
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_648 KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.19
Category members Pathway Pathway_685 PID_RAS_PATHWAY 0 0.14
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0032045 guanyl-nucleotide exchange factor complex Database 0.04
Category members Pathway Pathway_387 ST_T_CELL_SIGNAL_TRANSDUCTION 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000165 MAPK cascade Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0005088 Ras guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0019992 diacylglycerol binding Database 0
Category members GO Category GO:0032854 positive regulation of Rap GTPase activity Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0043087 regulation of GTPase activity Database 0
Category members GO Category GO:0046582 Rap GTPase activator activity Database 0


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