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Query: IFITM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IFITM1 0 -2.054 0.560 -0.530
IFITM1 0 -2.054 1.200 -0.770

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IFITM1 Ubiquitylation K3 -0.716 -1.338 _M(ox)HK(gl)EEHEVAVLGPPPSTILPR_

Background Information for IFITM1:





Protein-protein Interactions for IFITM1

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in IFITM1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CD225/Dispanin_fam IPR007593 0


Protein complexes (CORUM database) featuring IFITM1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IFITM1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members Pathway Pathway_648 KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.19
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0035455 response to interferon-alpha Database 0.08
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0035456 response to interferon-beta Database 0.03
Category members Pathway Pathway_1218 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL 0 0
Category members Pathway Pathway_913 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING 0 0
Category members GO Category GO:0001503 ossification Database 0
Category members GO Category GO:0005057 receptor signaling protein activity Database 0
Category members GO Category GO:0009607 response to biotic stimulus Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0034341 response to interferon-gamma Database 0
Category members GO Category GO:0045071 negative regulation of viral genome replication Database 0
Category members GO Category GO:0045669 positive regulation of osteoblast differentiation Database 0
Category members GO Category GO:0046597 negative regulation of viral entry into host cell Database 0
Category members GO Category GO:0050776 regulation of immune response Database 0
Category members GO Category GO:0060337 type I interferon signaling pathway Database 0


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