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positive regulation of fibroblast proliferation
(GO:0048146)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
XRCC4 1 -0.240 0.070
PDGFA 1 0.190 -0.340 -2.109 1.885
UTS2 0 -0.560 0.180 -0.048 0.360
FOSL2 0 0.940 -0.940
CDK6 0 -0.190 0.160
CDK6 0 -0.190 0.160 -0.510 0.013
ZMIZ1 0 1.370 -0.740
WNT5A 0
CDKN1A 0 1.080 -0.750
CDK4 0 1.930 -0.950
CDK4 0 1.930 -0.950 -0.510 0.013
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
CCNA2 0 -0.530 0.260
EGFR 0 -0.580 0.520 0.513 0.090
FBRS 0 1.380 -0.490
FBRS 0 1.380 -0.490
NDUFS4 0 0.190 -0.590 -0.148 -0.106
BMI1 0 0.900 -1.150 0.182
ANXA2 0 -1.230 1.610
ANXA2 0 -0.830 1.020
ANXA2 0 -0.740 0.850
ANXA2 0 -1.230 1.610 -0.075 0.002 -0.652 0.608 0.330
ANXA2 0 -0.830 1.020 -0.075 0.002 -0.652 0.608 0.330
ANXA2 0 -0.740 0.850 -0.075 0.002 -0.652 0.608 0.330
GAS6 0 0.020 0.220 -1.517 -0.502
MIF 0 1.480 -0.910 -0.887 -0.872 -1.709 0.653
FNTB 0

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ANXA2 Phosphorylation S12 0.179 _(ac)STVHEILCKLS(ph)LEGDHSTPPSAYGSVK_
ANXA2 Phosphorylation T19 0.015 -0.422 _LSLEGDHST(ph)PPSAYGSVK_
ANXA2 Phosphorylation S22 -0.273 -1.050 _LSLEGDHSTPPS(ph)AYGSVK_
ANXA2 Phosphorylation Y24 -1.100 _LSLEGDHSTPPSAY(ph)GSVK_
ANXA2 Phosphorylation S26 -0.518 -0.691 _LSLEGDHSTPPSAYGS(ph)VK_
ANXA2 Ubiquitylation K49 0.729 _TK(gl)GVDEVTIVNILTNR_
ANXA2 Ubiquitylation K148 0.314 1.024 _VYK(gl)EMYK_
ANXA2 Ubiquitylation K176 -0.855 0.760 _LMVALAK(gl)GR_
ANXA2 Ubiquitylation K204 0.375 1.026 _DLYDAGVK(gl)R_
ANXA2 Ubiquitylation K206 -0.599 _DLYDAGVK(gl)RK_
ANXA2 Ubiquitylation K302 0.390 _SEVDMLK(gl)IR_
ANXA2 Ubiquitylation K324 0.768 0.350 _SLYYYIQQDTK(gl)GDYQK_
CCNA2 Ubiquitylation K54 -0.746 _AALAVLK(gl)SGNPR_
CCNA2 Ubiquitylation K68 -1.274 _GLAQQQRPK(gl)TR_
CDK4 Ubiquitylation K142 -0.552 _DLK(gl)PENILVTSGGTVK_
CDK4 Ubiquitylation K211 -0.101 _K(gl)PLFCGNSEADQLGK_
CDK4 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Ubiquitylation K297 0.247 0.052 _ALQHSYLHK(gl)DEGNPE_
CDK4 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK4 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK4 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK4 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK4 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK4 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK4 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK4 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDK6 Ubiquitylation K3 0.121 0.039 _(ac)MEK(gl)DGLCR_
CDK6 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK6 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK6 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK6 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK6 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK6 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK6 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK6 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDKN1A Ubiquitylation K188 -2.505 -1.077 _QTSMTDFYHSK(gl)R_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
FBRS Phosphorylation S177 0.640 0.272 _VS(ph)PFGLR_
FBRS Phosphorylation T428 -1.042 _T(ph)PPGALLGAPPPLVPAPR_
FBRS Phosphorylation S447 -1.458 -1.873 _PS(ph)SPPRGPGPAR_
FBRS Phosphorylation S448 -1.544 -0.923 _PSS(ph)PPRGPGPAR_
FNTB Phosphorylation S3 -0.680 -0.936 _(ac)AS(ph)PSSFTYYCPPSSSPVWSEPLYSLRPEHAR_
FOSL2 Phosphorylation S200 -0.517 _S(ph)PPAPGLQPMR_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MIF Ubiquitylation K78 0.018 0.329 _SYSK(gl)LLCGLLAER_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_
XRCC4 Ubiquitylation K178 0.552 _EALETDLYK(gl)R_
XRCC4 Ubiquitylation K197 0.264 _SLHNK(gl)LLNAAQER_
XRCC4 Phosphorylation S259 -0.552 1.634 _DDSIIS(ph)SLDVTDIAPSR_
XRCC4 Phosphorylation S260 -0.545 1.299 _DDSIISS(ph)LDVTDIAPSR_
XRCC4 Phosphorylation S320 0.439 1.683 _KEHISAENM(ox)S(ph)LETLR_
ZMIZ1 Ubiquitylation K559 -0.155 _SVLQGLLKK(gl)_


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