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Query: PPP2R5A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPP2R5A 0 0.516 -0.210 0.930

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPP2R5A Phosphorylation S5 -0.414 _(ac)SSSS(ph)PPAGAASAAISASEK_

Background Information for PPP2R5A:


Pubmed-PPP2R5A »
Uniprot-PPP2R5A »
Biogrid-PPP2R5A »
ProteomicsDB-PPP2R5A »

Tumorportal-PPP2R5A »
COSMIC-PPP2R5A »
GenomeRNAi-PPP2R5A »
Genecards-PPP2R5A


Protein-protein Interactions for PPP2R5A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PPP2CA Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM43A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MOS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP2CB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRR14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPP2R5A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members PP2A_B56 IPR002554 0


Protein complexes (CORUM database) featuring PPP2R5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2998 Axin-PP2A A-PP2A C-GSK3-beta-beta-catenin complex Database 0.06


Categories featuring PPP2R5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_807 REACTOME_SIGNALING_BY_WNT 0 2.74
Category members Pathway Pathway_223 KEGG_OOCYTE_MEIOSIS 0 2.71
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members Pathway Pathway_1257 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE 0 1.21
Category members Pathway Pathway_936 REACTOME_CTLA4_INHIBITORY_SIGNALING 0 0.77
Category members Pathway Pathway_671 PID_WNT_CANONICAL_PATHWAY 0 0.64
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0030018 Z disc Database 0.32
Category members Pathway Pathway_720 REACTOME_PLATELET_SENSITIZATION_BY_LDL 0 0.29
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members Pathway Pathway_858 PID_MYC_PATHWAY 0 0.17
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members Pathway Pathway_285 REACTOME_PLATELET_HOMEOSTASIS 0 0.08
Category members Pathway Pathway_620 REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY 0 0.06
Category members Pathway Pathway_209 PID_DELTA_NP63_PATHWAY 0 0
Category members GO Category GO:0000159 protein phosphatase type 2A complex Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008601 protein phosphatase type 2A regulator activity Database 0
Category members GO Category GO:0031430 M band Database 0
Category members GO Category GO:0035307 positive regulation of protein dephosphorylation Database 0


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