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Query: IFT122

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IFT122 0 -0.172 0.590 -0.240
IFT122 0 -0.172 1.590 -0.690

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IFT122 Ubiquitylation K804 -0.101 _MLITK(gl)QADWAR_
IFT122 Ubiquitylation K1084 -0.071 _FQK(gl)SIELGTLTIR_

Background Information for IFT122:


Pubmed-IFT122 »
Uniprot-IFT122 »
Biogrid-IFT122 »
ProteomicsDB-IFT122 »

Tumorportal-IFT122 »
COSMIC-IFT122 »
GenomeRNAi-IFT122 »
Genecards-IFT122


Protein-protein Interactions for IFT122
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DNAJC7 Cat. description Hein, Mann, Cell 2015
Category members IP bait VANGL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARHGEF16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf74 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf179 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IARS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFT122 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IFT122
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members Quino_amine_DH_bsu IPR011044 0


Protein complexes (CORUM database) featuring IFT122
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IFT122
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0035721 intraciliary retrograde transport Database 0.09
Category members Disease phenotype Cranioectodermal_dysplasia Cranioectodermal dysplasia Database 0.01
Category members GO Category GO:0001843 neural tube closure Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0009953 dorsal/ventral pattern formation Database 0
Category members GO Category GO:0010172 embryonic body morphogenesis Database 0
Category members GO Category GO:0030991 intraciliary transport particle A Database 0
Category members GO Category GO:0032391 photoreceptor connecting cilium Database 0
Category members GO Category GO:0035050 embryonic heart tube development Database 0
Category members GO Category GO:0042733 embryonic digit morphogenesis Database 0
Category members GO Category GO:0045879 negative regulation of smoothened signaling pathway Database 0
Category members GO Category GO:0048593 camera-type eye morphogenesis Database 0
Category members GO Category GO:0060173 limb development Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0
Category members GO Category GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway Database 0
Category members GO Category GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning Database 0


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