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Query: EVL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EVL 0 1.177 0.030 -0.430
EVL 0 1.177 0.030 -0.430 0.413 0.435 0.673

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EVL Phosphorylation S349 0.089 1.311 _TPSVAKS(ph)PEAK_
EVL Phosphorylation S329 0.147 0.356 _S(ph)NSVEKPVSSILSR_
EVL Phosphorylation S331 0.246 0.219 _SNS(ph)VEKPVSSILSR_
EVL Phosphorylation S246 -0.996 0.095 _VQRPEDASGGSS(ph)PSGTSK_
EVL Ubiquitylation K483 -1.901 _GSTIETEQKEDKGEDSEPVTSK(gl)ASSTSTPEPTR_

Background Information for EVL:


Pubmed-EVL »
Uniprot-EVL »
Biogrid-EVL »
ProteomicsDB-EVL »

Tumorportal-EVL »
COSMIC-EVL »
GenomeRNAi-EVL »
Genecards-EVL


Protein-protein Interactions for EVL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PAPSS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EVL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAP1L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVRL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZYX Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EVL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ran_bind_dom IPR000156 2.46
Category members VASP_tetra IPR014885 0.29
Category members Vasodilator_phosphoprotein IPR017354 0.09
Category members WH1/EVH1 IPR000697 0


Protein complexes (CORUM database) featuring EVL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EVL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0046907 intracellular transport Database 3.25
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008154 actin polymerization or depolymerization Database 0.47
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0005522 profilin binding Database 0.44
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_701 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES 0 0.22
Category members Pathway Pathway_573 REACTOME_TCR_SIGNALING 0 0.2
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0007015 actin filament organization Database 0.08
Category members Pathway Pathway_1031 REACTOME_SIGNALING_BY_ROBO_RECEPTOR 0 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0009887 organ morphogenesis Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0


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