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Query: RASAL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RASAL2 0 2.444 1.030 0.010

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RASAL2 Phosphorylation S237 0.731 1.380 _S(ph)HESLLSPCSTVECLDLGR_
RASAL2 Phosphorylation S164 1.064 -0.013 _S(ph)ISGTSTSEKPNSMDTANTSPFK_
RASAL2 Phosphorylation S159 -0.749 -0.405 _LEVPAERS(ph)PR_
RASAL2 Phosphorylation S134 -0.988 -0.690 _TVS(ph)VPSEGQFPEYPPEGATK_
RASAL2 Phosphorylation T132 -1.010 _T(ph)VSVPSEGQFPEYPPEGATK_
RASAL2 Phosphorylation T761 -0.307 _SLTNPT(ph)PIQQQLR_

Background Information for RASAL2:





Protein-protein Interactions for RASAL2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKRD28 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP78 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK1E Cat. description Hein, Mann, Cell 2015
Category members IP bait MGP Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCI Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SHC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RASAL2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members RasGAP IPR001936 0.19
Category members PH_domain IPR001849 0.14
Category members PP1_inhibitor IPR008025 0.04
Category members C2_dom IPR000008 0
Category members DUF3498 IPR021887 0


Protein complexes (CORUM database) featuring RASAL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5233 TNF-alpha/NF-kappa B signaling complex 5 Database 0.29


Categories featuring RASAL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0032320 positive regulation of Ras GTPase activity Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0046580 negative regulation of Ras protein signal transduction Database 0.23
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0005099 Ras GTPase activator activity Database 0.02
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0031235 intrinsic to cytoplasmic side of plasma membrane Database 0
Category members GO Category GO:0042325 regulation of phosphorylation Database 0


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