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JAK-STAT cascade
(GO:0007259)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
CTR9 2 -0.230 0.260 1.648 -0.448 0.795
CTR9 2 -0.230 0.260 0.905 1.607
STAMBP 1 -1.500 2.650
IFNAR1 1 -1.770 3.060
PKD1 0 -0.900 0.980
PIAS1 0 -1.020 1.720 -1.034 -0.678 0.471 -0.051 1.019
FGFR3 0 -1.120 1.390
STAT1 0 -0.550 0.170
IFNAR2 0 0.700 -0.450
STAT3 0 0.200 -1.270 0.334
STAT5B 0 0.670 -0.960

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CTR9 Ubiquitylation K770 -0.112 _LATSVLK(gl)DEK_
CTR9 Ubiquitylation K844 0.845 _AK(gl)QEQEKELLR_
CTR9 Phosphorylation T925 0.431 0.460 _KGGEFDEFVNDDT(ph)DDDLPISK_
CTR9 Phosphorylation S970 -0.260 0.024 _GEEGS(ph)DDDETENGPKPK_
FGFR3 Ubiquitylation K205 -0.115 _IGGIK(gl)LR_
IFNAR1 Ubiquitylation K86 -0.259 _LSGCQNITSTK(gl)CNFSSLK_
IFNAR1 Phosphorylation S495 -0.050 _NLLLSTS(ph)EEQIEK_
IFNAR2 Phosphorylation S400 -0.542 -0.094 _RKS(ph)PLQDPFPEEDYSSTEGSGGR_
PIAS1 Ubiquitylation K60 -1.191 _AGCSPAVQMKIK(gl)_
PIAS1 Ubiquitylation K341 -1.248 _VSLLCPLGK(gl)MR_
PIAS1 Phosphorylation S490 -0.898 -0.944 _RTCPSLSPTS(ph)PLNNK_
PIAS1 Phosphorylation S505 0.198 -0.250 _GILSLPHQAS(ph)PVSR_
PKD1 Phosphorylation T867 0.841 _GT(ph)YHVRLEVNNTVSGAAAQADVR_
STAMBP Ubiquitylation K96 -0.832 _LK(gl)EIAFPK_
STAMBP Ubiquitylation K107 0.530 -0.048 _AEELK(gl)AELLK_
STAMBP Ubiquitylation K144 -0.041 _NMAIQQELEK(gl)EK_
STAMBP Ubiquitylation K146 -0.693 _NMAIQQELEKEK(gl)QR_
STAMBP Ubiquitylation K180 0.159 _LK(gl)IVQEFGK_
STAT1 Phosphorylation S727 1.377 0.974 _LQTTDNLLPMS(ph)PEEFDEVSR_
STAT3 Ubiquitylation K177 0.957 _VVENLQDDFDFNYK(gl)TLK_
STAT3 Ubiquitylation K180 1.179 _TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3 Ubiquitylation K244 0.262 _TLTDEELADWK(gl)R_
STAT3 Phosphorylation T714 -0.338 _FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3 Phosphorylation S727 -0.079 0.156 _FICVTPTTCSNTIDLPMS(ph)PR_
STAT5B Phosphorylation S194 0.270 _IQAQFGPLAQLS(ph)PQER_


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