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Query: IFNAR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IFNAR1 1 2.751 -1.770 3.060

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IFNAR1 Phosphorylation S495 -0.050 _NLLLSTS(ph)EEQIEK_
IFNAR1 Ubiquitylation K86 -0.259 _LSGCQNITSTK(gl)CNFSSLK_

Background Information for IFNAR1:


Pubmed-IFNAR1 »
Uniprot-IFNAR1 »
Biogrid-IFNAR1 »
ProteomicsDB-IFNAR1 »

Tumorportal-IFNAR1 »
COSMIC-IFNAR1 »
GenomeRNAi-IFNAR1 »
Genecards-IFNAR1


Protein-protein Interactions for IFNAR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BTRC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFNB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF10A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IFNAR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Fibronectin_type3 IPR003961 0.19
Category members Interferon_alpha/beta_rcpt_bsu IPR015373 0


Protein complexes (CORUM database) featuring IFNAR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 552 IFNB1-IFNAR1-IFNAR2- complex Database 0.21


Categories featuring IFNAR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_448 KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION 0 2.05
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members Pathway Pathway_447 KEGG_JAK_STAT_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0032729 positive regulation of interferon-gamma production Database 0.08
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0004905 type I interferon receptor activity Database 0.05
Category members GO Category GO:0042110 T cell activation Database 0.02
Category members Pathway Pathway_1096 BIOCARTA_RANKL_PATHWAY 0 0
Category members Pathway Pathway_1224 REACTOME_REGULATION_OF_IFNA_SIGNALING 0 0
Category members Pathway Pathway_1225 ST_TYPE_I_INTERFERON_PATHWAY 0 0
Category members Pathway Pathway_612 KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_646 KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 0 0
Category members Pathway Pathway_897 PID_CD8_TCR_DOWNSTREAM_PATHWAY 0 0
Category members Pathway Pathway_913 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING 0 0
Category members GO Category GO:0004904 interferon receptor activity Database 0
Category members GO Category GO:0007259 JAK-STAT cascade Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0045351 type I interferon biosynthetic process Database 0
Category members GO Category GO:0060337 type I interferon signaling pathway Database 0
Category members GO Category GO:0060338 regulation of type I interferon-mediated signaling pathway Database 0


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