Results for the Category
REACTOME_REGULATION_OF_IFNA_SIGNALING
(Pathway_1224)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
IFNAR1 | 1 | -1.770 | 3.060 | |||||
STAT1 | 0 | -0.550 | 0.170 | |||||
IFNAR2 | 0 | 0.700 | -0.450 | |||||
JAK1 | 0 | 0.190 | -0.100 | -1.504 | -0.381 | -0.438 | ||
PTPN1 | 0 | -0.150 | 0.310 | 1.066 | 0.459 | 0.251 | 0.322 | 0.379 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
IFNAR1 | Ubiquitylation | K86 | -0.259 | _LSGCQNITSTK(gl)CNFSSLK_ | |
IFNAR1 | Phosphorylation | S495 | -0.050 | _NLLLSTS(ph)EEQIEK_ | |
IFNAR2 | Phosphorylation | S400 | -0.542 | -0.094 | _RKS(ph)PLQDPFPEEDYSSTEGSGGR_ |
JAK1 | Ubiquitylation | K227 | -0.405 | _YIPETLNK(gl)SIR_ | |
JAK1 | Ubiquitylation | K249 | 0.116 | 0.771 | _DFLK(gl)EFNNK_ |
JAK1 | Ubiquitylation | K559 | -0.478 | _EISNLLVATK(gl)K_ | |
PTPN1 | Phosphorylation | S352 | 0.032 | _GS(ph)PLNAAPYGIESMSQDTEVR_ | |
PTPN1 | Phosphorylation | S365 | -0.247 | 0.956 | _GSPLNAAPYGIESMS(ph)QDTEVR_ |
PTPN1 | Phosphorylation | S378 | 1.462 | 1.262 | _VVGGS(ph)LR_ |
STAT1 | Phosphorylation | S727 | 1.377 | 0.974 | _LQTTDNLLPMS(ph)PEEFDEVSR_ |
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