Results for the Category
receptor internalization
(GO:0031623)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| LDLRAP1 | 2 | 0.870 | -0.890 | |||||
| DNM2 | 1 | 0.440 | -0.080 | 1.049 | -1.435 | 1.593 | 1.013 | |
| DNM2 | 1 | 0.440 | -0.080 | 0.076 | ||||
| EZR | 1 | -0.240 | -0.210 | 2.501 | -2.209 | 0.246 | 0.091 | |
| DNM1 | 1 | -0.280 | 0.150 | 1.049 | -1.435 | 1.593 | 1.013 | |
| ARRB2 | 1 | 2.000 | -1.160 | -0.340 | 0.096 | 0.051 | -1.604 | |
| NEDD4 | 0 | -1.320 | 1.730 | |||||
| PICALM | 0 | 0.890 | -0.980 | 0.221 | 0.666 | |||
| PICALM | 0 | 0.890 | -0.980 | |||||
| CLTC | 0 | 0.350 | -0.220 | -0.538 | -0.243 | -0.478 | 0.375 | 0.284 |
| RAB31 | 0 | -0.330 | -0.520 | 0.590 | ||||
| RAB31 | 0 | -0.330 | -0.520 | 0.223 | ||||
| ADRBK1 | 0 | -0.390 | 0.360 | |||||
| ADRBK1 | 0 | -0.340 | 0.480 | |||||
| ULK1 | 0 | 0.740 | -0.520 | |||||
| GRB2 | 0 | -0.240 | 0.300 | -1.021 | 0.057 | 0.906 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ADRBK1 | Phosphorylation | S670 | 1.038 | 0.924 | _NKPRS(ph)PVVELSK_ |
| ADRBK1 | Phosphorylation | S676 | 1.113 | _NKPRSPVVELS(ph)K_ | |
| ARRB2 | Ubiquitylation | K199 | -1.933 | _VQFAPEK(gl)PGPQPSAETTR_ | |
| CLTC | Ubiquitylation | K83 | 0.714 | _VIALK(gl)AGK_ | |
| CLTC | Ubiquitylation | K86 | 0.631 | _VIALKAGK(gl)_ | |
| CLTC | Ubiquitylation | K389 | -1.051 | -0.085 | _VAANAPK(gl)GILR_ |
| CLTC | Phosphorylation | T394 | -0.123 | 0.181 | _GILRT(ph)PDTIRR_ |
| CLTC | Ubiquitylation | K506 | 0.267 | _IVLYAK(gl)K_ | |
| CLTC | Ubiquitylation | K507 | 0.050 | 0.267 | _IVLYAKK(gl)_ |
| CLTC | Ubiquitylation | K619 | -0.177 | 0.475 | _AHIAQLCEK(gl)AGLLQR_ |
| CLTC | Ubiquitylation | K737 | -0.435 | -0.298 | _YIQAACK(gl)TGQIK_ |
| CLTC | Ubiquitylation | K742 | 0.005 | 0.082 | _TGQIK(gl)EVER_ |
| CLTC | Ubiquitylation | K851 | -0.859 | _GQFSTDELVAEVEK(gl)R_ | |
| CLTC | Ubiquitylation | K911 | -1.282 | _YCEK(gl)RDPHLACVAYER_ | |
| CLTC | Ubiquitylation | K1118 | -0.674 | -0.765 | _AQLQK(gl)GMVK_ |
| CLTC | Ubiquitylation | K1209 | -0.791 | _CYDEK(gl)MYDAAK_ | |
| CLTC | Ubiquitylation | K1443 | -2.089 | -0.019 | _VK(gl)QLPLVKPYLR_ |
| CLTC | Ubiquitylation | K1449 | -2.307 | _QLPLVK(gl)PYLR_ | |
| CLTC | Ubiquitylation | K1516 | -0.990 | _IAAYLFK(gl)GNNR_ | |
| CLTC | Ubiquitylation | K1609 | -0.714 | _EYLTK(gl)VDKLDASESLR_ | |
| DNM1 | Ubiquitylation | K393 | 0.542 | _EISYAIK(gl)NIHGVR_ | |
| DNM1 | Phosphorylation | S764 | -2.106 | -1.205 | _EALNIIGDISTSTVSTPVPPPVDDTWLQSASSHS(ph)PTPQR_ |
| DNM2 | Ubiquitylation | K393 | 0.542 | _EISYAIK(gl)NIHGVR_ | |
| DNM2 | Phosphorylation | S764 | -2.106 | -1.205 | _EALNIIGDISTSTVSTPVPPPVDDTWLQSASSHS(ph)PTPQR_ |
| EZR | Ubiquitylation | K3 | -0.313 | -0.251 | _PK(gl)PINVR_ |
| EZR | Ubiquitylation | K79 | 0.172 | -0.032 | _ENPLQFK(gl)FR_ |
| EZR | Ubiquitylation | K139 | 1.519 | 0.361 | _FGDYNK(gl)EVHK_ |
| EZR | Ubiquitylation | K162 | 1.580 | 0.660 | _VMDQHK(gl)LTR_ |
| EZR | Ubiquitylation | K253 | -0.069 | _NISFNDK(gl)K_ | |
| EZR | Ubiquitylation | K263 | -0.786 | _K(gl)APDFVFYAPR_ | |
| EZR | Ubiquitylation | K344 | 0.598 | 0.235 | _EK(gl)EELMLR_ |
| EZR | Ubiquitylation | K357 | -0.003 | _LQDYEEK(gl)TK_ | |
| EZR | Ubiquitylation | K359 | 0.051 | _LQDYEEK(gl)TK_ | |
| EZR | Ubiquitylation | K450 | 0.393 | 0.174 | _AK(gl)EAQDDLVK_ |
| GRB2 | Ubiquitylation | K10 | 0.146 | _YDFK(gl)ATADDELSFK_ | |
| GRB2 | Ubiquitylation | K20 | -0.078 | _ATADDELSFK(gl)R_ | |
| GRB2 | Ubiquitylation | K69 | -0.362 | 0.641 | _AK(gl)AEEMLSK_ |
| GRB2 | Ubiquitylation | K76 | 0.754 | _AEEMLSK(gl)QR_ | |
| GRB2 | Ubiquitylation | K109 | 0.381 | -0.002 | _FGNDVQHFK(gl)VLR_ |
| LDLRAP1 | Ubiquitylation | K5 | 6.085 | 8.895 | _(ac)MDALK(gl)SAGR_ |
| LDLRAP1 | Phosphorylation | S14 | -0.662 | 0.149 | _ALIRS(ph)PSLAK_ |
| NEDD4 | Phosphorylation | Y751 | -0.924 | _RGSLQAY(ph)TFEEQPTLPVLLPTSSGLPPGWEEK_ | |
| NEDD4 | Ubiquitylation | K874 | 0.127 | _LK(gl)IPAHLR_ | |
| NEDD4 | Ubiquitylation | K882 | -0.919 | 0.114 | _GK(gl)TSLDTSNDLGPLPPGWEER_ |
| PICALM | Ubiquitylation | K210 | -0.364 | 0.811 | _YLNEK(gl)AVSYR_ |
| PICALM | Phosphorylation | T294 | -0.800 | _KPHTSLT(ph)TAASPVSTSAGGIM(ox)TAPAIDIFSTPSSSNSTSK_ | |
| RAB31 | Phosphorylation | S36 | 0.043 | 0.209 | _FVQDHFDHNIS(ph)PTIGASFMTK_ |
| RAB31 | Ubiquitylation | K178 | -0.542 | _RIPSTDANLPSGGK(gl)GFK_ | |
| RAB31 | Ubiquitylation | K181 | -0.651 | _RIPSTDANLPSGGK(gl)GFK_ | |
| ULK1 | Phosphorylation | S450 | -0.237 | -0.173 | _NLQS(ph)PTQFQTPR_ |
| ULK1 | Phosphorylation | T468 | -0.247 | 0.456 | _SGST(ph)SPLGFAR_ |
| ULK1 | Phosphorylation | S469 | 0.035 | 0.470 | _SGSTS(ph)PLGFAR_ |
| ULK1 | Phosphorylation | S623 | -0.793 | -0.874 | _NPLPPILGS(ph)PTK_ |
| ULK1 | Phosphorylation | T625 | -0.547 | -0.776 | _NPLPPILGSPT(ph)K_ |
| ULK1 | Phosphorylation | T636 | 0.087 | _T(ph)PSSQNLLALLAR_ | |
| ULK1 | Phosphorylation | S638 | -0.154 | 0.598 | _TPS(ph)SQNLLALLAR_ |
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© Copyright Svejstrup Laboratory 2015